During heavy exercise in chronic obstructive pulmonary disease (COPD), dynamic airways
compression leads to a progressive fall in intrabreath flow. This is manifested by concavity in …

IN HUMANS, EXPIRATION during quiet breathing is usually considered passive, since
expiratory muscles are not active. Expiration is driven by elastic energy stored in the …

Active expiration during exercise can increase intrathoracic pressure yielding concavity in
the expiratory flow-volume loop in COPD. We investigated the relationship between this …

Maximal expiratory flow–volume (MEFV) curve evaluation using absolute and percent
predicted values of flow and volume are used to diagnose respiratory disease, but the shape …

Study objective Estimating lung volume using inspiratory capacity (IC) maneuvers is a useful
way of tracking dynamic hyperinflation. An understanding of the repeatability of the IC in a …

The inspiratory capacity (IC) maneuver is increasingly used to monitor exercise-induced
dynamic hyperinflation in patients with COPD. However, the reliability of this method in …

Background Severe hyperinflation causes detrimental effects such as dyspnea and reduced
exercise capacity and is an independent predictor of mortality in COPD patients. Static lung …

Tidal volume at peak exercise and vital capacity ratio (VTpeak/VC) and VTpeak/inspiratory
capacity (IC) were used to differentiate lung expansion in subjects with normal health and …

This short review summarizes a series of studies on the effects of expiratory flow limitation
(EFL) at∼ 1 L/s during incremental exercise to maximal workload (Wmax) in normal subjects …

We assessed the relationship between minute ventilation/carbon dioxide output (VE/VCO 2)
and ventilatory constraints during an incremental cardiopulmonary exercise testing (CPET) …