Allergen Immunotherapy (AIT) was introduced in clinical practice on an empirical basis more
than 100 years ago. Since the first attempts, AIT was administered subcutaneously. Indeed …

Background Allergic rhinitis is a common condition which, at its most severe, can
significantly impair quality of life despite optimal treatment with antihistamines and topical …

BACKGROUND: Subcutaneous (SCIT) and sublingual (SLIT) immunotherapy are the 2 most
prescribed routes for administering allergen-specific immunotherapy. They were shown to …

Subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) are both
effective treatments for allergic rhinitis and allergic asthma, both show clinical evidence of …

To cite this article: Calderón MA, Simons FER, Malling H‐J, Lockey RF, Moingeon P, Demoly
P. Sublingual allergen immunotherapy: mode of action and its relationship with the safety …

BACKGROUND: Sublingual immunotherapy (SLIT) is increasingly being used for the
treatment of allergic rhinitis, but there are conflicting study results demonstrating clinically …

Allergic rhinitis (AR) and nonallergic rhinopathy (NAR) represent common nasal conditions
affecting millions of individuals across the world. Although patients present with similar …

BACKGROUND: Severe allergic rhinitis uncontrolled by pharmacotherapy can adversely
affect quality of life. Both subcutaneous immunotherapy (SCIT) and sublingual …

BACKGROUND: Subcutaneous allergen-specific immunotherapy (SIT) has an early onset of
action, whereas repeated injections and safety concerns have limited its use in the pediatric …

Subcutaneous immunotherapy and sublingual immunotherapy are beneficial in treating
allergic rhinitis and venom hypersensitivity but should be administered only by physicians …