Aspirin resistance

HA Tran, SS Anand, GJ Hankey, JW Eikelboom - Thrombosis research, 2007 - Elsevier
Aspirin resistance refers to less than expected suppression of thromboxane A2 production
by aspirin and has been reported to be independently associated with an increased risk of …

Aspirin resistance: current concepts.

PJ Mason, JE Freedman, AK Jacobs - Reviews in cardiovascular …, 2004 - europepmc.org
Aspirin is an effective antiplatelet agent with proven benefit in the prevention of
atherothrombotic complications of cardiovascular disease. The antithrombotic effects of …

Aspirin resistance: position paper of the Working Group on Aspirin Resistance

AD Michelson, M Cattaneo, JW Eikelboom… - Journal of Thrombosis …, 2005 - jthjournal.org
Conclusions The correct treatment, if any, of aspirin 'resistance'is unknown. No published
studies address the clinical effectiveness of altering therapy based on a laboratory finding of …

Clinical implications of aspirin resistance

N Zimmermann, T Hohlfeld - Thrombosis and haemostasis, 2008 - thieme-connect.com
Aspirin reduces major atherothrombotic events across a wide spectrum of patients with
atherosclerotic disease. The occurrence of ischemic events despite of aspirin treatment is a …

Aspirin resistance: what, why and when?

E Shantsila, T Watson, GYH Lip - Thrombosis research, 2007 - thrombosisresearch.com
There is a perception that up to 40% of aspirin users may be resistant to aspirin, and given
the widespread use of this drug to reduce cardiovascular risk, could this mean that large …

Clinical implications of aspirin resistance

D Patel, M Moonis - Expert Review of Cardiovascular Therapy, 2007 - Taylor & Francis
Aspirin (acetylsalicylic acid) is one of the main therapeutic medications used in the
prevention of thromboembolic vascular events. Aspirin exhibits its antiplatelet action by …

Aspirin resistance

GJ Hankey, JW Eikelboom - The Lancet, 2006 - thelancet.com
Aspirin resistance is the inability of aspirin to reduce platelet production of thromboxane A 2
and thereby platelet activation and aggregation. Increasing degrees of aspirin resistance …

Aspirin resistance: mechanisms and clinical implications

C Hanjis, WH Frishman, RG Lerner - Cardiology in Review, 2006 - journals.lww.com
Acetylsalicylic acid (aspirin) has been shown to irreversibly interfere with platelet function,
an effect that is associated with a reduction in morbid and mortal arterial thrombotic events in …

Aspirin resistance: definitions, mechanisms, prevalence, and clinical significance

L Macchi, N Sorel, L Christiaens - Current pharmaceutical …, 2006 - ingentaconnect.com
Aspirin is the most commonly used therapeutic agent in prevention of vascular ischemic
events. Aspirin exerts its antithrombotic effect primarily by interfering with the biosynthesis of …

[HTML][HTML] Aspirin resistance

A Szczeklik, J Musiał, A Undas, M Sanak - Journal of Thrombosis and …, 2005 - Elsevier
Treatment failures occur with any drug and aspirin is no exception. Evidence is growing to
indicate that there are subpopulations that do not respond to antithrombotic action of aspirin …