Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women
DJ Thompson, CS Healey, C Baynes… - … Biomarkers & Prevention, 2008 - AACR
Background: Circulating levels of sex hormone-binding globulin (SHBG) are inversely
associated with breast cancer risk in postmenopausal women. Three polymorphisms within …
associated with breast cancer risk in postmenopausal women. Three polymorphisms within …
Prospective association of serum androgens and sex hormone-binding globulin with subclinical cardiovascular disease in young adult women: the “Coronary Artery …
R Calderon-Margalit, SM Schwartz… - The Journal of …, 2010 - academic.oup.com
Context: The role of endogenous androgens and SHBG in the development of
cardiovascular disease in young adult women is unclear. Objective: Our objective was to …
cardiovascular disease in young adult women is unclear. Objective: Our objective was to …
Sex hormone-binding globulin, genetic susceptibility, and the risk of type 2 diabetes in men and postmenopausal women
W Zhang, H Zhang, B Wang, Y Wang… - Chinese Medical …, 2023 - mednexus.org
To the Editor: Type 2 diabetes (T2D) is one of the most common and fastest growing non-
communicable diseases worldwide. Sex hormone-binding globulin (SHBG) is a circulating …
communicable diseases worldwide. Sex hormone-binding globulin (SHBG) is a circulating …
[HTML][HTML] Sex hormone-binding globulin and heart failure hospitalizations in patients with dysglycemia: Experiences from the outcome reduction with an Initial Glargine …
A Wang, S Hess, SF Lee, HC Gerstein - Diabetes Research and Clinical …, 2023 - Elsevier
Introduction Sex hormone-binding globulin (SHBG), which binds most of circulating
testosterone in blood, has been linked to dysglycemia and cardiovascular disease but the …
testosterone in blood, has been linked to dysglycemia and cardiovascular disease but the …
Sex hormones and the risk of myocardial infarction in women and men: a prospective cohort study in the UK Biobank
K Harris, SAE Peters, M Woodward - Biology of sex Differences, 2023 - Springer
Objectives There is conflicting evidence around the role of sex hormones with
cardiovascular outcomes. The aim of this study was to examine the association of sex …
cardiovascular outcomes. The aim of this study was to examine the association of sex …
Sex hormone–binding globulin as an independent predictor of incident type 2 diabetes mellitus in men
KM Lakshman, S Bhasin… - Journals of Gerontology …, 2010 - academic.oup.com
Background. Low levels of sex hormone–binding globulin (SHBG) and total testosterone (T)
in men have been associated with increased risk of type 2 diabetes mellitus (T2DM). As total …
in men have been associated with increased risk of type 2 diabetes mellitus (T2DM). As total …
Sex hormone levels–estradiol, testosterone, and sex hormone binding globulin as a risk marker for atherosclerotic coronary artery disease in post-menopausal …
DV Das, UK Saikia, D Sarma - Indian journal of endocrinology and …, 2019 - journals.lww.com
Aims: To investigate the relationship between sex hormones (estradiol and testosterone)/sex
hormone binding globulin (SHBG) and cardiovascular risk factors in PM women. In addition …
hormone binding globulin (SHBG) and cardiovascular risk factors in PM women. In addition …
The relationship of sex hormone-binding globulin (SHBG) gene polymorphisms with serum SHBG level and metabolic syndrome in Chinese Han males
XN Pang, Y Yuan, Y Sun, JP Shen, XY Zha… - Aging Clinical and …, 2014 - Springer
Objective Epidemiological studies have shown that circulating sex hormone-binding
globulin (SHBG) levels are lower in metabolic syndrome (MetS) patients than in non-MetS …
globulin (SHBG) levels are lower in metabolic syndrome (MetS) patients than in non-MetS …
Low levels of sex hormone-binding globulin predict an increased breast cancer risk and its underlying molecular mechanisms
S Zhao, J Gu, Y Tian, R Wang, W Li - Open Life Sciences, 2024 - degruyter.com
Sex hormone-binding globulin (SHBG) is a serum glycoprotein exhibiting the unique feature
of binding sex steroids with high affinity and specificity. Over the past few decades, there …
of binding sex steroids with high affinity and specificity. Over the past few decades, there …
Associations between serum sex hormone concentrations and whole blood gene expression profiles in the general population
Background Despite observational evidence from epidemiological and clinical studies
associating sex hormones with various cardiometabolic risk factors or diseases …
associating sex hormones with various cardiometabolic risk factors or diseases …