Unravelling the adiponectin paradox: novel roles of adiponectin in the regulation of cardiovascular disease

L Woodward, I Akoumianakis… - British journal of …, 2017 - Wiley Online Library
Adipose tissue (AT) has recently been identified as a dynamic endocrine organ secreting a
wide range of adipokines. Adiponectin is one such hormone, exerting endocrine and …

Adiponectin and cardiovascular health: an update

X Hui, KSL Lam, PM Vanhoutte… - British journal of …, 2012 - Wiley Online Library
The global epidemic of obesity is accompanied by an increased prevalence of
cardiovascular disease (CVD), in particular stroke and heart attack. Dysfunctional adipose …

Adiponectin and cardiovascular disease: mechanisms and new therapeutic approaches

G Siasos, D Tousoulis, C Kollia… - Current medicinal …, 2012 - ingentaconnect.com
Adiponectin is an abundant plasma protein secreted from adipocytes. Its role in energy
homeostasis is well-known, including the regulation of hydrocarbons and lipids metabolism …

Back to the heart: the protective role of adiponectin

C Caselli, A D'amico, M Cabiati, T Prescimone… - Pharmacological …, 2014 - Elsevier
Cardiovascular disease (CVD) is the leading cause of death worldwide and the prevalence
of obesity and diabetes are increasing. In obesity, adipose tissue increases the secretion of …

Adiponectin: from obesity to cardiovascular disease

C Antoniades, AS Antonopoulos, D Tousoulis… - obesity …, 2009 - Wiley Online Library
Adiponectin is an adipokine whose biosynthesis is deranged in obesity and diabetes
mellitus, predisposing to atherosclerosis. Evidence suggests that adiponectin has anti …

Examining the potential of developing and implementing use of adiponectin-targeted therapeutics for metabolic and cardiovascular diseases

Y Liu, V Vu, G Sweeney - Frontiers in endocrinology, 2019 - frontiersin.org
Cardiometabolic diseases encompass those affecting the heart and vasculature as well as
other metabolic problems, such as insulin resistance, diabetes, and non-alcoholic fatty liver …

Adiponectin: mechanistic insights and clinical implications

AT Turer, PE Scherer - Diabetologia, 2012 - Springer
Adiponectin is an adipocyte-derived secretory protein that has been very widely studied over
the past 15 years. A multitude of different functions have been attributed to this adipokine. It …

The role of adiponectin in cardiovascular disease

J Peng, Q Chen, C Wu - Cardiovascular Pathology, 2023 - Elsevier
Cardiovascular disease (CVD) is a common disease that seriously threatens the health of
human beings, especially middle-aged and elderly people over 50 years old. It has the …

Adiponectin and cardiovascular disease: state of the art?

PE Szmitko, H Teoh, DJ Stewart… - American Journal of …, 2007 - journals.physiology.org
The cardiometabolic syndrome, associated with increased cardiovascular disease risk in the
industrialized world, is estimated to affect one in four adults. Although the mechanisms …

Protective role of adiponectin in cardiovascular disease

R Shibata, T Murohara, N Ouchi - Current medicinal chemistry, 2012 - ingentaconnect.com
This review focuses on the recent findings that adiponectin plays a significant role of in
cardiovascular diseases. Adipose tissue functions as an endocrine organ by secreting …