Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas

M Krajewska, SF Moss, S Krajewski, KI Song, PR Holt… - Cancer Research, 1996 - AACR
Expression of several members of the BCL-2 family of genes was investigated by
immunohistochemical methods in 30 primary colorectal adenocarcinomas and 24 …

Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases.

OI Olopade, MO Adeyanju, AR Safa… - The cancer journal …, 1997 - europepmc.org
Purpose Dysregulation of genes that control apoptosis can contribute to tumor progression
and increased drug resistance. The BCL2 gene and its family member BCL-x as well as the …

Bcl‐2 protooncogene expression in cervical carcinoma cell lines containing inactive p53

XH Liang, S Mungal, A Ayscue… - Journal of cellular …, 1995 - Wiley Online Library
Bcl‐2 protein expression has been found to block apoptosis and its overexpression has
been implicated in lymphoid malignancies where the chromosomal translocation t (14; 18) is …

Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death

PL Simonian, DAM Grillot… - Blood, The Journal of the …, 1997 - ashpublications.org
Bcl-2 and its homologue Bcl-XL are expressed in a variety of tumors and their expression
modulates the sensitivity of tumor cells to a wide spectrum of chemotherapeutic agents and γ …

Differential regulation of p53, c-Myc, Bcl-2 and Bax protein expression during apoptosis induced by widely divergent stimuli in human hepatoblastoma cells.

MC Jiang, HF Yang-Yen, JK Lin, JJ Yen - Oncogene, 1996 - europepmc.org
Apoptosis of HepG2 cells triggered by various agents is characterized in an attempt to
delineate the common apoptosis signaling pathway in human hepatoma cells. Several …