Epstein‐Barr virus‐driven metabolic alterations contribute to the viral lytic reactivation and tumor progression in nasopharyngeal carcinoma
F Shi, L Shang, M Zhou, C Lv, Y Li… - Journal of Medical …, 2024 - Wiley Online Library
Metabolic reprogramming induced by Epstein‐Barr virus (EBV) often mirrors metabolic
changes observed in cancer cells. Accumulating evidence suggests that lytic reactivation is …
changes observed in cancer cells. Accumulating evidence suggests that lytic reactivation is …
EBV infection and its regulated metabolic reprogramming in nasopharyngeal tumorigenesis
T Yang, C You, S Meng, Z Lai, W Ai… - Frontiers in Cellular and …, 2022 - frontiersin.org
Viral oncogenes may drive cellular metabolic reprogramming to modulate the normal
epithelia cell malignant transformation. Understanding the viral oncogene–mediated …
epithelia cell malignant transformation. Understanding the viral oncogene–mediated …
EBV infection and glucose metabolism in nasopharyngeal carcinoma
To establish persistent infection in cells, viruses evolve strategies to alter host cellular
pathways to regulate cell proliferation and energy metabolism which support viral infection …
pathways to regulate cell proliferation and energy metabolism which support viral infection …
Targeting Epstein–Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy
Our goal in this work was to illustrate the Epstein-Barr virus (EBV)-modulated global
biochemical profile and provide a novel metabolism-related target to improve the therapeutic …
biochemical profile and provide a novel metabolism-related target to improve the therapeutic …
Cytolytic virus activation therapy and treatment monitoring for Epstein‐Barr virus associated nasopharyngeal carcinoma in a mouse tumor model
Z Novalić, SAWM Verkuijlen, M Verlaan… - Journal of Medical …, 2017 - Wiley Online Library
Undifferentiated nasopharyngeal carcinoma (NPC) is 100% associated with Epstein‐Barr
virus (EBV). Expression of viral proteins in the tumor cells is highly restricted. EBV …
virus (EBV). Expression of viral proteins in the tumor cells is highly restricted. EBV …
Targeting Epstein-Barr virus in nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is consistently associated with Epstein-Barr virus (EBV)
infection in regions in which it is endemic, including Southern China and Southeast Asia …
infection in regions in which it is endemic, including Southern China and Southeast Asia …
EBV abortive lytic cycle promotes nasopharyngeal carcinoma progression through recruiting monocytes and regulating their directed differentiation
X Xu, N Zhu, J Zheng, Y Peng, MS Zeng, K Deng… - Plos …, 2024 - journals.plos.org
Epstein-Barr virus (EBV) is associated with several types of human cancer including
nasopharyngeal carcinoma (NPC). The activation of EBV to the lytic cycle has been …
nasopharyngeal carcinoma (NPC). The activation of EBV to the lytic cycle has been …
Perspective: contribution of epstein–barr virus (EBV) reactivation to the carcinogenicity of nasopharyngeal cancer cells
CC Wu, CY Fang, SY Huang, SH Chiu, CH Lee… - Cancers, 2018 - mdpi.com
Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma derived from the
epithelium of the post-nasal cavity, with a unique geographic and ethnic distribution. Epstein …
epithelium of the post-nasal cavity, with a unique geographic and ethnic distribution. Epstein …
Intermittent abortive reactivation of Epstein-Barr virus during the progression of nasopharyngeal cancer as indicated by elevated antibody levels
X Guo, T Li, F Li, Y Xu, H Wang, W Cheng, J Tang… - Oral Oncology, 2019 - Elsevier
The development of nasopharyngeal carcinoma (NPC), a common cancer in Southeastern
Asia, is closely associated with Epstein-Barr virus (EBV) infection; however, the aetiological …
Asia, is closely associated with Epstein-Barr virus (EBV) infection; however, the aetiological …
DNMT1 mediates metabolic reprogramming induced by Epstein–Barr virus latent membrane protein 1 and reversed by grifolin in nasopharyngeal carcinoma
X Luo, L Hong, C Cheng, N Li, X Zhao, F Shi… - Cell Death & …, 2018 - nature.com
Cancer cells frequently adapt fundamentally altered metabolism to support tumorigenicity
and malignancy. Epigenetic and metabolic networks are closely interactive, in which DNA …
and malignancy. Epigenetic and metabolic networks are closely interactive, in which DNA …
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