OBJECTIVE: To determine the existence of a soluble signal, secreted from the human
blastocyst embryo, that induces HOXA10 gene expression before cell–cell contact. DESIGN …

Carbon monoxide (CO), formed during heme oxygenase (HO)-catalyzed oxidation of heme,
has been proposed to play a complementary role with nitric oxide in the regulation of …

HOX genes are transcriptional regulators that play an essential role in determining tissue
identity during embryonic development. HOX genes are involved in the development of the …

Somatic cell-embryo coculture enhances embryo development in vitro by producing
embryotrophic factor (s) and/or removing harmful substances from the culture environment …

Defective differentiation of invasive, placental trophoblast cells has been associated with
several pregnancy-related disorders. This study examines the molecular, functional, and …

During embryo implantation, the outer layer of the blastocyst interacts with the endometrium
giving rise to the development of the trophoblast cell lineage. The cells in this lineage …

Abstract Purpose To investigate the Homeobox genes HOXA-10 and HOXA-11 mediated
endometrial molecular defects during implantation window in endometriosis-associated …

Early embryonic development occurs under low oxygen levels. The placenta is an organ
transiently formed during pregnancy and plays a crucial role during development of the …

Infiltrating myeloid cells in pregnant uteri play critical roles in the establishment of the
placenta and maintenance of normal pregnancies. Their recruitment and proliferation are …

Objective To examine endogenous heme oxygenase (HO) expression on the surface of
placental trophoblasts of pregnant women who had a fetus with intrauterine growth …