The role of epigenetics and non-coding RNAs in autophagy: A new perspective for thorough understanding

S Talebian, H Daghagh, B Yousefi, Y Ȍzkul… - Mechanisms of ageing …, 2020 - Elsevier
Autophagy is a major self-degradative intracellular process required for the maintenance of
homeostasis and promotion of survival in response to starvation. It plays critical roles in a …

Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer

SP Kolapalli, TM Nielsen, LB Frankel - Cell Death & Differentiation, 2023 - nature.com
Autophagy is an essential recycling and quality control pathway which preserves cellular
and organismal homeostasis. As a catabolic process, autophagy degrades damaged and …

Transcriptional and post-transcriptional regulation of autophagy

Q Ma, S Long, Z Gan, G Tettamanti, K Li, L Tian - Cells, 2022 - mdpi.com
Autophagy is a widely conserved process in eukaryotes that is involved in a series of
physiological and pathological events, including development, immunity, neurodegenerative …

The update on transcriptional regulation of autophagy in normal and pathologic cells: A novel therapeutic target

Z Zhang, M Guo, S Zhao, W Xu, J Shao, F Zhang… - Biomedicine & …, 2015 - Elsevier
Autophagy is a genetically programmed, evolutionarily conserved catabolic process that
occurs in response to stress. While short-lived proteins are degraded via the …

Epigenetic regulation of autophagy

LF Hu - Autophagy: Biology and Diseases: Basic Science, 2019 - Springer
Epigenetics refers to reversible and hereditary changes in gene expression without
alterations in DNA sequences, such as DNA methylation, histone modification and …

Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress

YS Yu, H Kim, KI Kim, SH Baek - Cell Death & Differentiation, 2023 - nature.com
Autophagy is an evolutionarily conserved catabolic process that is induced in response to
various stress factors in order to protect cells and maintain cellular homeostasis by …

Epigenetic and post-translational modifications in autophagy: biological functions and therapeutic targets

F Shu, H Xiao, QN Li, XS Ren, ZG Liu, BW Hu… - … and Targeted Therapy, 2023 - nature.com
Autophagy is a conserved lysosomal degradation pathway where cellular components are
dynamically degraded and re-processed to maintain physical homeostasis. However, the …

Exploring the role of non-coding RNAs in autophagy

S Ghafouri-Fard, H Shoorei, M Mohaqiq, J Majidpoor… - Autophagy, 2022 - Taylor & Francis
As a self-degradative mechanism, macroautophagy/autophagy has a role in the
maintenance of energy homeostasis during critical periods in the development of cells. It …

Regulation of mammalian autophagy in physiology and pathophysiology

B Ravikumar, S Sarkar, JE Davies… - Physiological …, 2010 - journals.physiology.org
(Macro) autophagy is a bulk degradation process that mediates the clearance of long-lived
proteins and organelles. Autophagy is initiated by double-membraned structures, which …

Transcriptional regulation of autophagy and its implications in human disease

Y Lei, DJ Klionsky - Cell Death & Differentiation, 2023 - nature.com
Macroautophagy/autophagy is a conserved catabolic pathway that is vital for maintaining
cell homeostasis and promoting cell survival under stressful conditions. Dysregulation of …