Clostridium difficile Whole Genome Sequencing Reveals Limited Transmission Among Symptomatic Children: A Single-Center Analysis
LK Kociolek, DN Gerding, RO Espinosa… - Clinical infectious …, 2018 - academic.oup.com
Abstract Background Although pediatric Clostridium difficile infections (CDIs) are increasing,
C. difficile transmission patterns among children are poorly understood. Methods We …
C. difficile transmission patterns among children are poorly understood. Methods We …
Molecular epidemiology of Clostridium difficile infections in children: a retrospective cohort study
LK Kociolek, SJ Patel, ST Shulman… - infection control & …, 2015 - cambridge.org
OBJECTIVEThe molecular epidemiology of pediatric Clostridium difficile infection (CDI) is
poorly understood. We aimed to identify the restriction endonuclease analysis (REA) groups …
poorly understood. We aimed to identify the restriction endonuclease analysis (REA) groups …
Molecular Epidemiology and Genetic Relatedness of Clostridioides difficile Isolates in Pediatric Oncology and Transplant Patients Using Whole Genome Sequencing
R Barbar, JN Brazelton, KC Carroll… - Clinical Infectious …, 2023 - academic.oup.com
Abstract Background The incidence of Clostridioides difficile infection (CDI) has been rising
among hospitalized children, with poor understanding of genomic variability of C. difficile …
among hospitalized children, with poor understanding of genomic variability of C. difficile …
Patient and Strain Characteristics Associated With Clostridium difficile Transmission and Adverse Outcomes
JSH Martin, DW Eyre, WN Fawley… - Clinical Infectious …, 2018 - academic.oup.com
Background No study has used whole-genome sequencing (WGS) to investigate risk factors
for Clostridium difficile (CD) transmission between cases, or assessed the impact of recent …
for Clostridium difficile (CD) transmission between cases, or assessed the impact of recent …
Clinical and Microbiological Characteristics of Clostridium difficile Infection Among Hospitalized Children in the Netherlands
SM van Dorp, E Smajlović, CW Knetsch… - Clinical Infectious …, 2017 - academic.oup.com
Background. Little is known about pediatric Clostridium difficile infection (CDI) epidemiology.
We describe the clinical and microbiological characteristics of CDI among hospitalized …
We describe the clinical and microbiological characteristics of CDI among hospitalized …
Clostridium difficile: Investigating Transmission Patterns Between Infected and Colonized Patients Using Whole Genome Sequencing
Background Whole genome sequencing (WGS) studies can enhance our understanding of
the role of patients with asymptomatic Clostridium difficile colonization in transmission …
the role of patients with asymptomatic Clostridium difficile colonization in transmission …
Clostridium difficile Infection Among Children Across Diverse US Geographic Locations
JM Wendt, JA Cohen, Y Mu, GK Dumyati, JR Dunn… - …, 2014 - publications.aap.org
OBJECTIVE: Little is known about the epidemiology of Clostridium difficile infection (CDI)
among children, particularly children≤ 3 years of age in whom colonization is common but …
among children, particularly children≤ 3 years of age in whom colonization is common but …
Whole-genome analysis reveals the evolution and transmission of an MDR DH/NAP11/106 Clostridium difficile clone in a paediatric hospital
LK Kociolek, EA Ozer, DN Gerding… - Journal of …, 2018 - academic.oup.com
Background Clostridium difficile strain DH/NAP11/106, a relatively antibiotic-susceptible
strain, is now the most common cause of C. difficile infection (CDI) among adults in the USA …
strain, is now the most common cause of C. difficile infection (CDI) among adults in the USA …
Whole‐genome sequencing links Clostridium (Clostridioides) difficile in a single hospital to diverse environmental sources in the community
Abstract Aims To investigate if Clostridium (Clostridioides) difficile infection (CDI),
traditionally thought of as hospital‐acquired, can be genomically linked to hospital or …
traditionally thought of as hospital‐acquired, can be genomically linked to hospital or …
Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing
Background It has been thought that Clostridium difficile infection is transmitted
predominantly within health care settings. However, endemic spread has hampered …
predominantly within health care settings. However, endemic spread has hampered …
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