Synthesis and antitumor application of antiangiogenetic gold nanoclusters

Q Li, R Zhou, Y Sun, D Xiao, M Liu… - … Applied Materials & …, 2021 - ACS Publications
Conventional antiangiogenetic inhibitors suffered from poor delivery problems that result in
unsatisfactory antitumor treatment efficacy. Although the liposomes or nanomaterial-based …

Gold nanoparticles induce nanostructural reorganization of VEGFR2 to repress angiogenesis

Y Pan, H Ding, L Qin, X Zhao, J Cai… - Journal of biomedical …, 2013 - ingentaconnect.com
The inhibition of the binding between VEGFs and their receptors reduces angiogenesis and
retards tumor growth. Owing to the large amount of antibodies required, the antibody-based …

Preparation, pharmacokinetic and application of gold nanoclusters (AuNCs) in tumor treatment

T Yang, J Zhang, Y Yu, T Sun - Current Medicinal Chemistry, 2021 - benthamdirect.com
As a new type of nanomaterials, the gold nanoclusters (AuNCs) perform many special
physical and chemical properties, such as large Stokes shift, relatively simple preparation …

In situ biosynthesized gold nanoclusters inhibiting cancer development via the PI3K–AKT signaling pathway

M Wang, Z Yu, H Feng, J Wang, L Wang… - Journal of Materials …, 2019 - pubs.rsc.org
Nanomaterials have made great breakthroughs in drug delivery. However, in previous
studies, nanomaterials have been mostly used as vehicles to transport drugs into tumors …

Gold nanoparticles as antiangiogenic and antimetastatic agents

A Zamborlin, V Voliani - Drug Discovery Today, 2023 - Elsevier
Highlights•Invasion and metastases are central features of cancer malignancy and constitute
the primary cause of death for> 90% of patients with cancer.•The establishment of effective …

Radiosynthesis of Stable 198Au-Nanoparticles by Neutron Activation of αvβ3-Specific AuNPs for Therapy of Tumor Angiogenesis

G Davarci, C Wängler, K Eberhardt, C Geppert… - Pharmaceuticals, 2023 - mdpi.com
This paper reports on the development of stable tumor-specific gold nanoparticles (AuNPs)
activated by neutron irradiation as a therapeutic option for the treatment of cancer with high …

Biosynthesis of flower-shaped Au nanoclusters with EGCG and their application for drug delivery

S Wu, X Yang, F Luo, T Wu, P Xu, M Zou… - Journal of …, 2018 - Springer
Background In the last decade, the biosynthesis of metal nanoparticles using organisms
have received more and more considerations. However, the complex composition of …

Peptide-coated gold nanoparticles for modulation of angiogenesis in vivo

C Roma-Rodrigues, A Heuer-Jungemann… - International journal …, 2016 - Taylor & Francis
In this work, peptides designed to selectively interact with cellular receptors involved in the
regulation of angiogenesis were anchored to oligo-ethylene glycol-capped gold …

Engineering ultrasmall water-soluble gold and silver nanoclusters for biomedical applications

Z Luo, K Zheng, J Xie - Chemical communications, 2014 - pubs.rsc.org
Gold and silver nanoclusters or Au/Ag NCs with core sizes smaller than 2 nm have been an
attractive frontier of nanoparticle research because of their unique physicochemical …

Synthesis and study of cell-penetrating peptide-modified gold nanoparticles

F Boussoufi, SMN Gallón, R Chang… - International journal of …, 2018 - Taylor & Francis
Background In nanomedicine, gold nanoparticles (AuNPs) have demonstrated versatile
therapeutic efficiencies and, in particular, have been developed for the treatment of various …