The papillary carcinoma family (PCF) of thyroid tumors includes a wide variety of neoplastic
entities regarded as well-differentiated, poorly differentiated, and undifferentiated papillary …

Background. The expression of RET/PTC chimeras was demonstrated in 10% to 20% of
sporadic papillary thyroid carcinomas (PTCs), whereas rearrangements ofNTRK 1 were …

Rearrangement of the RET gene, also known as RET/PTC rearrangement, is the most
common genetic alteration identified to date in thyroid papillary carcinomas. The prevalence …

The prevalence of RET/PTC rearrangements in papillary thyroid carcinomas (PTCs) varies
widely in different studies, and an association of RET/PTC presence with tumor behavior …

Malignant tumors of the thyroid gland vary considerably in aggressiveness, ranging from a
well-differentiated, clinically indolent, to an undifferentiated, often lethal phenotype …

Among different genetic factors involved in the pathogenesis of the papillary thyroid
carcinoma (PTC), rearrangements of RET protooncogene (RET/PTC), as well as …

Objective RET proto-oncogene rearrangements (ret/PTCs) represent the most common
genetic alterations found in papillary thyroid carcinomas (PTCs). Correlation of ret/PTC …

The RET proto-oncogene encodes a cell membrane tyrosine-kinase receptor protein whose
ligands belong to the glial cell line–derived neurotrophic factor. RET functions as a …

Context: RET/PTC rearrangements have been reported in papillary thyroid carcinomas with
variable frequency in studies that used different detection methods. Objective: Our objective …

BACKGROUND The frequency of RET rearrangements (RET/PTC) in papillary thyroid
carcinomas varies significantly according to geographic area, with the greatest incidence …