Dysfunction of circadian and sleep rhythms is an early feature of many neurodegenerative
diseases. Alzheimer's disease (AD) is a progressive neurodegenerative disorder resulting in …

Aging leads to changes in circadian rhythms, including decreased amplitude or robustness,
altered synchrony with the environment, and reduced coordination of rhythms within body …

Alzheimer's disease (AD) is a neurodegenerative disease that accounts for most cases of
dementia. Besides progressive cognitive decline, circadian dysfunction is a prominent …

Sleep–wake cycles are known to be disrupted in people with neurodegenerative disorders.
These findings are now supported by data from animal models for some of these disorders …

Molecular and cellular oscillations constitute an internal clock that tracks the time of day and
permits organisms to optimize their behaviour and metabolism to suit the daily demands …

Alzheimer's disease (AD) is considered to be the most typical form of dementia that provokes
irreversible cognitive impairment. Along with cognitive impairment, circadian rhythm …

Circadian rhythms are physiological and behavioural cycles generated by an endogenous
biological clock, the suprachiasmatic nucleus. The circadian system influences the majority …

Disruptions of sleep and circadian rhythms are among the most debilitating symptoms in
patients with neurodegenerative diseases. Their underlying pathophysiology is multilayered …

Alzheimer's disease (AD) is one of the crucial causative factors for progressive dementia.
Neuropathologically, AD is characterized by the extracellular accumulation of amyloid beta …

Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the
most common type of dementia. Along with progressive cognitive impairment, dysfunction of …