Advances in immuno‐oncology have provided a variety of novel therapeutics that harness
the innate immune system to identify and destroy neoplastic cells. It is noteworthy that …

BACKGROUND We have entered a new era of cancer therapy, with a number of immune-
based therapies already used clinically as a standard of care. Adoptive cellular …

Immunotherapy has emerged as a crucial treatment option, particularly for types of cancer
that display resistance to conventional therapies. A remarkable breakthrough in this field is …

Cancer immunotherapy offers tremendous clinical outcomes in cancer management with the
potential to induce sustained remission in patients with refractory disease. One of these …

In this article, we reviewed the current literature studies and our understanding of the
parameters that affect the chimeric antigen receptor T cells (CAR-T's) activation, effector …

Chimeric antigen receptor T cell (CAR T cell) therapy has emerged as a prominent adoptive
cell therapy and a therapeutic approach of great interest in the fight against cancer. This …

Advances in the development of immunotherapies have offered exciting new options for the
treatment of malignant diseases that are refractory to conventional cytotoxic …

Background: Cancer is one of the leading causes of death worldwide. Chemotherapy,
radiation therapy, and stem cell transplantation were the main cancer treatment approaches …

Chimeric antigen receptor-T cells (CAR-Ts) are an exciting new cancer treatment modality
exemplified by the recent regulatory approval of two CD19-targeted CAR-T therapies for …

Simple Summary As a result of FDA approval of CAR-T cell treatments in the last few years,
this immunotherapy has provided further direction to precision medicine through its …