[PDF][PDF] Cell-based drug delivery devices using phagocytosis-resistant backpacks
MF Rubner, S Mitragotri - Adv Mater, 2011 - academia.edu
Macrophages, ubiquitous phagocytic cells in the human immune system, play a key role in
homeostatic, immunological, and inflammatory processes.[1–2] Macrophages are widely …
homeostatic, immunological, and inflammatory processes.[1–2] Macrophages are widely …
Recent advances in macrophage-mediated drug delivery systems
T Liang, R Zhang, X Liu, Q Ding, S Wu… - International journal …, 2021 - Taylor & Francis
Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …
they can prolong the circulation and release of drugs, extend their half-life, increase their …
Cellular backpacks for macrophage immunotherapy
Adoptive cell transfers have emerged as a disruptive approach to treat disease in a manner
that is more specific than using small-molecule drugs; however, unlike traditional drugs …
that is more specific than using small-molecule drugs; however, unlike traditional drugs …
Macrophage cell membrane‐cloaked nanoplatforms for biomedical applications
J Lopes, D Lopes, M Pereira‐Silva, D Peixoto… - Small …, 2022 - Wiley Online Library
Biomimetic approaches utilize natural cell membrane‐derived nanovesicles to camouflage
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …
Monocyte-mediated delivery of polymeric backpacks to inflamed tissues: a generalized strategy to deliver drugs to treat inflammation
Targeted delivery of drugs and imaging agents to inflamed tissues, as in the cases of cancer,
Alzheimer's disease, Parkinson's disease, and arthritis, represents one of the major …
Alzheimer's disease, Parkinson's disease, and arthritis, represents one of the major …
Advancements in macrophage-targeted drug delivery for effective disease management
H Liu, H Lv, X Duan, Y Du, Y Tang… - International Journal of …, 2023 - Taylor & Francis
Macrophages play a crucial role in tissue homeostasis and the innate immune system. They
perform essential functions such as presenting antigens, regulating cytokines, and …
perform essential functions such as presenting antigens, regulating cytokines, and …
Nanoparticle‐laden macrophages for tumor‐tropic drug delivery
Macrophages hold great potential in cancer drug delivery because they can sense
chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …
chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …
Neutrophils enable local and non‐invasive liposome delivery to inflamed skeletal muscle and ischemic heart
Uncontrolled inflammation is a major pathological factor underlying a range of diseases
including autoimmune conditions, cardiovascular disease, and cancer. Improving localized …
including autoimmune conditions, cardiovascular disease, and cancer. Improving localized …
Living leukocyte‐based drug delivery systems
Leukocytes play a vital role in immune responses, including defending against invasive
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …
Targeted drug delivery to macrophages
Introduction: Targeted drug delivery to the macrophages appears to be an attractive
proposition to improve therapeutic efficacy of enclosed drug. Thus, macrophages can be …
proposition to improve therapeutic efficacy of enclosed drug. Thus, macrophages can be …