Kidney dysfunction and cadmium exposure–factors influencing dose–response relationships
Our early toxicological studies showed that metallothionein (MT) is a protein that carries
cadmium (Cd) to the kidney, explaining why Cd exposures during long time periods may …
cadmium (Cd) to the kidney, explaining why Cd exposures during long time periods may …
Prevalence of kidney dysfunction in humans–relationship to cadmium dose, metallothionein, immunological and metabolic factors
Long term cadmium (Cd) exposure in occupational and general environments may give rise
to kidney dysfunction. This effect is usually considered to be the critical effect, ie the effect …
to kidney dysfunction. This effect is usually considered to be the critical effect, ie the effect …
Critical exposure level of cadmium for elevated urinary metallothionein—an occupational population study in China
L Chen, T Jin, B Huang, G Nordberg… - Toxicology and applied …, 2006 - Elsevier
Cadmium is a well-known nephrotoxic agent with extremely long biological half-time of 15–
30 years in humans. To prevent nephrotoxicity induced by cadmium, it is necessary to …
30 years in humans. To prevent nephrotoxicity induced by cadmium, it is necessary to …
[HTML][HTML] A polymorphism in metallothionein 1A (MT1A) is associated with cadmium-related excretion of urinary beta 2‐microglobulin
L Lei, X Chang, G Rentschler, L Tian, G Zhu… - Toxicology and applied …, 2012 - Elsevier
OBJECTIVES: Cadmium (Cd) toxicity of the kidney varies between individuals despite
similar exposure levels. In humans Cd is mainly bound to metallothioneins (MT), which …
similar exposure levels. In humans Cd is mainly bound to metallothioneins (MT), which …
The association between renal tubular dysfunction and zinc level in a Chinese population environmentally exposed to cadmium
X Chen, Z Wang, G Zhu, GF Nordberg, X Ding… - Biological Trace Element …, 2018 - Springer
Studies in vivo and in vitro have shown a protective effect of zinc against renal dysfunction
caused by cadmium exposure. However, limited human data is available. In this study, we …
caused by cadmium exposure. However, limited human data is available. In this study, we …
Cadmium and human health: a perspective based on recent studies in China
G Nordberg - The Journal of Trace Elements in Experimental …, 2003 - Wiley Online Library
Cadmium (Cd) occurs in low concentrations in all human diets and in cigarettes. In
contaminated areas and in certain occupations, high human exposures occur. In assessing …
contaminated areas and in certain occupations, high human exposures occur. In assessing …
Historical perspectives on cadmium toxicology
GF Nordberg - Toxicology and applied pharmacology, 2009 - Elsevier
The first health effects of cadmium (Cd) were reported already in 1858. Respiratory and
gastrointestinal symptoms occurred among persons using Cd-containing polishing agent …
gastrointestinal symptoms occurred among persons using Cd-containing polishing agent …
Excretion of urinary cadmium, copper, and zinc in cadmium-exposed and nonexposed subjects, with special reference to urinary excretion of β2-microglobulin and …
M Nakajima, E Kobayashi, Y Suwazono… - Biological trace element …, 2005 - Springer
The objectives of this study were to examine the association between urinary excretion of
cadmium (U-Cd) copper (U-Cu), and zinc (U-Zn) and the severity of two different indicators …
cadmium (U-Cd) copper (U-Cu), and zinc (U-Zn) and the severity of two different indicators …
Plasma metallothionein antibody and cadmium-induced renal dysfunction in an occupational population in China
L Chen, T Jin, B Huang, X Chang, L Lei… - Toxicological …, 2006 - academic.oup.com
It has been reported that anti-metallothionein (a metallothionein antibody) is present in the
circulation of healthy subjects and in patients suffering from atopic dermatitis. The aim of this …
circulation of healthy subjects and in patients suffering from atopic dermatitis. The aim of this …
The risk factors of blood cadmium elevation in chronic kidney disease
KF Tsai, PC Hsu, CT Kung, CT Lee, HL You… - International Journal of …, 2021 - mdpi.com
Low-level cadmium exposure has adverse effects on chronic kidney disease (CKD);
however, the risk factors for elevated blood cadmium levels (BCLs) have not been studied in …
however, the risk factors for elevated blood cadmium levels (BCLs) have not been studied in …