Generalized pustular psoriasis (GPP) represents the rarest form of psoriasis, which may be
potentially fatal. In the last decade,(likely) pathogenic variants in the IL36RN, CARD14 and …

Abstract Generalized Pustular Psoriasis (GPP) is a rare, severe, life-threatening form of
psoriasis and accounts for up to 13.1% of all childhood psoriasis. Common first-line systemic …

To evaluate the outcomes of secukinumab and acitretin use in children with generalized
pustular psoriasis (GPP), we compared the efficacy and adverse events of secukinumab in …

Juvenile generalized pustular psoriasis (GPP) is rare and often resistant to conventional
systemic therapy such as methotrexate, retinoic acid and cyclosporin A. GPP can be induced …

Generalized pustular psoriasis (GPP) is a rare but severe form of psoriasis. An early onset of
the diseases is correlated with mutations among IL36RN, CARD14, AP1S3, MPO and …

We report a case of a 3‐year‐old girl with generalized pustular psoriasis (GPP) and a
compound heterozygous mutation within the IL36 receptor antagonist (IL36RN) gene at c …

Background: Generalized pustular psoriasis (GPP) is a rare and life-threatening
autoinflammatory dermatological disease. IL36RN was reported to be the main pathogenetic …

Infantile pustular psoriasis (IPP) is an extremely rare skin disease associated with genetic
factors. Gene mutations of IL36RN (interleukin-36 receptor antagonist), CARD14 (caspase …

Generalized Pustular Psoriasis (GPP) is a dermatological autoinflammatory disease that
rarely occurs in children and is associated with complex genetic factors. GPP pathogenesis …

Generalized pustular psoriasis (GPP) is a potentially life‐threatening disease that can be
attributed to mutations in IL 36 RN in a subgroup of patients. In small trials, interleukin (IL) …