Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity
D Centonze, R Floris, M Stefanini, S Rossi… - Annals of …, 2011 - Wiley Online Library
Objective: It is still unclear whether chronic cerebrospinal venous insufficiency (CCSVI) is
associated with multiple sclerosis (MS), because substantial methodological differences …
associated with multiple sclerosis (MS), because substantial methodological differences …
Funding CCSVI research is/was a waste of valuable time, money and intellectual energy: yes
A Ghezzi - Multiple Sclerosis Journal, 2013 - journals.sagepub.com
In the case of CCSVI, all of these criteria are either not, or only partially, fulfilled: 5 a) the
discrepancy of results is against criterion 1; b) the lack of reproducibility against criterion 2 …
discrepancy of results is against criterion 1; b) the lack of reproducibility against criterion 2 …
[PDF][PDF] Analysis of patients with chronic cerebro-spinal venous insufficiency and multiple sclerosis: identification of parameters of clinical severity
S Mandolesi, A d'Alessandro, MM Ciccone… - Veins and …, 2015 - academia.edu
The aims of this study were: i) analysis of clinical severity evolution in multiple sclerosis
patients; ii) identification of temporal indicators for clinical worsening. We investigated by …
patients; ii) identification of temporal indicators for clinical worsening. We investigated by …
The perfect crime? CCSVI not leaving a trace in MS
CA Mayer, W Pfeilschifter, MW Lorenz… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background Multiple sclerosis (MS) is a chronic, inflammatory demyelinating disease of the
central nervous system, believed to be triggered by an autoimmune reaction to myelin …
central nervous system, believed to be triggered by an autoimmune reaction to myelin …
[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon
Background This study aimed to investigate the prevalence and clinical relevance of chronic
cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy …
cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy …
Brain hemodynamic changes associated with chronic cerebrospinal venous insufficiency are not specific to multiple sclerosis and do not increase its severity
FG Garaci, S Marziali, A Meschini, M Fornari, S Rossi… - Radiology, 2012 - pubs.rsna.org
Purpose To investigate the relationship between chronic cerebrospinal venous insufficiency
(CCSVI) and cerebral hemodynamic parameters and to disclose any possible involvement …
(CCSVI) and cerebral hemodynamic parameters and to disclose any possible involvement …
Occurrence of CCSVI in patients with MS and its relationship with iron metabolism and varicose veins
PJ Van den Berg, GB Van den Berg… - European journal of …, 2013 - Wiley Online Library
Background and purpose A new treatable venous disorder, chronic cerebrospinal venous
insufficiency (CCSVI), has been proposed in patients with multiple sclerosis (MS). Its …
insufficiency (CCSVI), has been proposed in patients with multiple sclerosis (MS). Its …
Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS
Background: Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in
patients with multiple sclerosis (MS). A subject is considered CCSVI positive if≥ 2 venous …
patients with multiple sclerosis (MS). A subject is considered CCSVI positive if≥ 2 venous …
Progressive multiple sclerosis is not associated with chronic cerebrospinal venous insufficiency
C Baracchini, P Perini, F Causin, M Calabrese… - Neurology, 2011 - AAN Enterprises
Objective: Chronic cerebrospinal venous insufficiency (CCSVI) had been suggested to play
a major pathogenetic role in multiple sclerosis (MS), but recent data on early stages of MS …
a major pathogenetic role in multiple sclerosis (MS), but recent data on early stages of MS …
Review and analysis of international Case-Control Studies on CCSVI and multiple sclerosis
C Krogias, G Tsivgoulis, M Grond, HP Hartung… - 2013 - mediatum.ub.tum.de
Background: A constellation of neurosonological findings called chronic cerebrospinal
venous insufficiency (CCSVI) was introduced as a highly specific and highly sensitive …
venous insufficiency (CCSVI) was introduced as a highly specific and highly sensitive …