Immunoregulatory paracrine effect of mesenchymal stem cells and mechanism in the treatment of osteoarthritis
X Zhang, T Liu, C Ran, W Wang, F Piao… - Frontiers in Cell and …, 2024 - frontiersin.org
Osteoarthritis (OA) is a degenerative joint disease caused by chronic inflammation that
damages articular cartilage. At present, the treatment of OA includes drug therapy to relieve …
damages articular cartilage. At present, the treatment of OA includes drug therapy to relieve …
[HTML][HTML] Mesenchymal stem cell-based therapy of osteoarthritis: Current knowledge and future perspectives
CR Harrell, BS Markovic, C Fellabaum… - Biomedicine & …, 2019 - Elsevier
Osteoarthritis (OA) is a chronic, prevalent, debilitating joint disease characterized by
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …
Mesenchymal stem cells: Current concepts in the management of inflammation in osteoarthritis
Osteoarthritis (OA) has traditionally been known as a “wear and tear” disease, which is
mainly characterized by the degradation of articular cartilage and changes in the …
mainly characterized by the degradation of articular cartilage and changes in the …
Effect of Arthritic Synovial Fluids on the Expression of Immunomodulatory Factors by Mesenchymal Stem Cells: An Explorative in vitro Study
MJC Leijs, GM Van Buul, E Lubberts, PK Bos… - Frontiers in …, 2012 - frontiersin.org
Background: In diseased joints, the catabolic environment results in progressive joint
damage. Mesenchymal stem cells (MSCs) can have immunomodulatory effects by secreting …
damage. Mesenchymal stem cells (MSCs) can have immunomodulatory effects by secreting …
Mesenchymal stem cell-based therapy for rheumatoid arthritis
M Sarsenova, A Issabekova, S Abisheva… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …
[HTML][HTML] Revolutionizing osteoarthritis treatment: How mesenchymal stem cells hold the key
R Tian, S Su, Y Yu, S Liang, C Ma, Y Jiao… - Biomedicine & …, 2024 - Elsevier
Osteoarthritis (OA) is a multifaceted disease characterized by imbalances in extracellular
matrix metabolism, chondrocyte and synoviocyte senescence, as well as inflammatory …
matrix metabolism, chondrocyte and synoviocyte senescence, as well as inflammatory …
Mesenchymal stromal cell immunology for efficient and safe treatment of osteoarthritis
M Najar, J Martel-Pelletier, JP Pelletier… - Frontiers in cell and …, 2020 - frontiersin.org
Mesenchymal stem cell (MSC) therapy represents a promising approach for the treatment of
osteoarthritis (OA). MSCs can be readily isolated from multiple sources and expanded ex …
osteoarthritis (OA). MSCs can be readily isolated from multiple sources and expanded ex …
Mesenchymal stem cells for cartilage repair in osteoarthritis
PK Gupta, AK Das, A Chullikana… - Stem cell research & …, 2012 - Springer
Osteoarthritis (OA) is a degenerative disease of the connective tissue and progresses with
age in the older population or develops in young athletes following sports-related injury. The …
age in the older population or develops in young athletes following sports-related injury. The …
Advances in mesenchymal stem cell therapy for osteoarthritis: from preclinical and clinical perspectives
Z Lv, X Cai, Y Bian, Z Wei, W Zhu, X Zhao, X Weng - Bioengineering, 2023 - mdpi.com
The prevalence of osteoarthritis (OA), a degenerative disorder of joints, has substantially
increased in recent years. Its key pathogenic hallmarks include articular cartilage …
increased in recent years. Its key pathogenic hallmarks include articular cartilage …
Mesenchymal stem cells regulate the innate and adaptive immune responses dampening arthritis progression
RA Contreras, FE Figueroa, F Djouad… - Stem Cells …, 2016 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent stem cells that are able to immunomodulate
cells from both the innate and the adaptive immune systems promoting an anti‐inflammatory …
cells from both the innate and the adaptive immune systems promoting an anti‐inflammatory …