Interplay between immunity and amyotrophic lateral sclerosis: Clinical impact

F De Marchi, I Munitic, A Amedei, JD Berry… - Neuroscience & …, 2021 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a debilitating and rapidly fatal neurodegenerative
disease. Despite decades of research and many new insights into disease biology over the …

Immunological drivers of amyotrophic lateral sclerosis

TF Gendron, L Petrucelli - Science translational medicine, 2023 - science.org
Amyotrophic lateral sclerosis (ALS), a devastating motor neuron disease involving complex
genetic and environmental factors, is associated with neuroinflammation. Preclinical and …

[HTML][HTML] The peripheral immune system and amyotrophic lateral sclerosis

PA McCombe, JD Lee, TM Woodruff… - Frontiers in …, 2020 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease that is defined by
loss of upper and lower motor neurons, associated with accumulation of protein aggregates …

[HTML][HTML] Immune modulation in the treatment of amyotrophic lateral sclerosis: a review of clinical trials

SI Khalid, L Ampie, R Kelly, SS Ladha… - Frontiers in neurology, 2017 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by the degeneration of motor neurons. Though many molecular and genetic …

Immunological aspects in amyotrophic lateral sclerosis

MCO Rodrigues, JC Voltarelli, PR Sanberg… - Translational stroke …, 2012 - Springer
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by
progressive motor neuron death, leading to muscle atrophy, paralysis, and death usually …

New insights on the disease contribution of neuroinflammation in amyotrophic lateral sclerosis

A Chiot, CS Lobsiger, S Boillée - Current Opinion in Neurology, 2019 - journals.lww.com
New insights on the disease contribution of neuroinflammatio... : Current Opinion in Neurology
New insights on the disease contribution of neuroinflammation in amyotrophic lateral sclerosis …

[HTML][HTML] The role of immune-mediated alterations and disorders in ALS disease

JR Lima-Junior, D Sulzer, CSL Arlehamn, A Sette - Human immunology, 2021 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that leads
to neuronal death in the brain and spinal cord. Over the last decades, evidence has …

[HTML][HTML] Peripheral and central nervous system immune response crosstalk in amyotrophic lateral sclerosis

Z Liu, X Cheng, S Zhong, X Zhang, C Liu… - Frontiers in …, 2020 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
muscle weakness due to the degeneration of the upper and lower motor neurons …

Inflammation, Immunity, and amyotrophic lateral sclerosis: I. Etiology and pathology

MS Lyon, M Wosiski‐Kuhn, R Gillespie… - Muscle & …, 2019 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a severely debilitating disease characterized by
progressive degeneration of motor neurons. Charcot first described ALS in 18691; however …

Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis

W Zhao, DR Beers, SH Appel - Journal of Neuroimmune Pharmacology, 2013 - Springer
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with
selective loss of upper and lower motor neurons. At sites of motor neuron injury …