Prospective study of the natural history of gastrinoma in patients with MEN1: definition of an aggressive and a nonaggressive form

F Gibril, DJ Venzon, JV Ojeaburu… - The Journal of …, 2001 - academic.oup.com
The natural history of pancreatic endocrine tumors (PETs) in patients with MEN1 is largely
unknown. Recent studies in patients with sporadic PETs show that in a subset, tumor growth …

Gastrinomas associated with MEN-1 syndrome: new insights for the diagnosis and management in a series of 11 patients.

GC Nikou, C Toubanakis, P Nikolaou… - Hepato …, 2005 - europepmc.org
Results At the time of presentation, 91% pts, had symptoms of peptic ulcer disease,
refractory to treatment, while a history of colicky abdominal pain due to nephrolithiasis was …

Screening for multiple endocrine neoplasia type 1 and hormonal production in apparently sporadic neuroendocrine tumors

E Baudin, JM Bidart, P Rougier, V Lazar… - The Journal of …, 1999 - academic.oup.com
Screening was performed in 130 consecutive patients with apparently sporadic
neuroendocrine tumors (NET) to assess the prevalence of multiple endocrine neoplasia type …

Genotype/phenotype correlation of multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas

SU Goebel, C Heppner, AL Burns… - The Journal of …, 2000 - academic.oup.com
Multiple endocrine neoplasia type 1 (MEN1) gene mutations are reported in some
gastrinomas occurring in patients without MEN1 as well as in some other pancreatic …

Precursor Lesions in Patients With Multiple Endocrine Neoplasia Type 1--Associated Duodenal Gastrinomas

M Anlauf, A Perren, CL Meyer, S Schmid… - Gastroenterology, 2005 - Elsevier
Background & Aims: The identification of precursor lesions has a great impact on the
understanding of tumorigenesis. Precursor lesions of endocrine tumors are known to occur …

Surgical treatment of the endocrine pancreas and Zollinger-Ellison syndrome in the MEN 1 syndrome

NW Thompson - Henry Ford Hospital Medical …, 1992 - scholarlycommons.henryford.com
Islet cell neoplasia is a frequent occurrence in multiple endocrine neoplasia type 1 (MEN 1).
Sixteen of 27 patients with MEN 1 developed functioning endocrine pancreatic tumor …

Gastric carcinoid tumors in multiple endocrine neoplasia-1 patients with Zollinger-Ellison syndrome can be symptomatic, demonstrate aggressive growth, and require …

JA Norton, ML Melcher, F Gibril, RT Jensen - Surgery, 2004 - Elsevier
BACKGROUND: Gastric carcinoid tumors occur in 15% to 50% of patients with multiple
endocrine neoplasia–1/Zollinger-Ellison syndrome (MEN-1/ZES) but are thought to be …

[HTML][HTML] Gastrinomas in the duodenums of patients with multiple endocrine neoplasia type 1 and the Zollinger-Ellison syndrome

M Pipeleers-Marichal, G Somers… - … England Journal of …, 1990 - Mass Medical Soc
In patients with multiple endocrine neoplasia type 1 (MEN-1), gastrinomas are common and
thought to occur predominantly in the pancreas. We describe eight patients with MEN-1 and …

MEN1 gene mutations in sporadic neuroendocrine tumors of foregut derivation

T Fujii, T Kawai, K Saito, T Hishima… - Pathology …, 1999 - Wiley Online Library
Foregut‐derived neuroendocrine (NE) tumors occur sporadically or in association with
multiple endocrine neoplasia type 1 (MEN1) syndrome. Thirty‐nine sporadic NE tumors of …

Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to …

B Görtz, J Roth, A Krähenmann, RR de Krijger… - The American journal of …, 1999 - Elsevier
Endocrine pancreatic tumors (EPT) and neuroendocrine tumors (NET) occur sporadically
and rarely in association with multiple endocrine neoplasia type 1 (MEN1). We analyzed the …