Design and discovery of new antibacterial agents: Advances, perspectives, challenges
J Jampilek - Current medicinal chemistry, 2018 - ingentaconnect.com
Background: Emerging resistance of bacterial pathogens to clinically used drugs, including
not only first-choice but also second-and third-choice drugs, is alarming, but since the 1990s …
not only first-choice but also second-and third-choice drugs, is alarming, but since the 1990s …
Synthetic antimicrobial peptidomimetics with therapeutic potential
BE Haug, W Stensen, M Kalaaji, Ø Rekdal… - Journal of medicinal …, 2008 - ACS Publications
A series of synthetic antimicrobial peptidomimetics (SAMPs) have been prepared and found
to be highly active against several Gram-negative and Gram-positive bacterial strains. These …
to be highly active against several Gram-negative and Gram-positive bacterial strains. These …
Characterization and in vitro Analysis of Probiotic-Derived Peptides Against Multi Drug Resistance Bacterial Infections
An inexorable switch from antibiotics has become a major desideratum to overcome
antibiotic resistance. Bacteriocin from Lactobacillus casei, a cardinal probiotic was used to …
antibiotic resistance. Bacteriocin from Lactobacillus casei, a cardinal probiotic was used to …
[HTML][HTML] Rationally designed antimicrobial peptides: Insight into the mechanism of eleven residue peptides against microbial infections
The widespread abuse of antibiotics has led to the use of antimicrobial peptides (AMPs) as a
replacement for the existing conventional therapeutic agents for combating microbial …
replacement for the existing conventional therapeutic agents for combating microbial …
Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
Medium-sized peptides from microbial sources with potential for antibacterial drug development
J Chen, W Wang, X Hu, Y Yue, X Lu, C Wang… - Natural Product …, 2024 - pubs.rsc.org
Covering: 1993 to the end of 2022As the rapid development of antibiotic resistance shrinks
the number of clinically available antibiotics, there is an urgent need for novel options to fill …
the number of clinically available antibiotics, there is an urgent need for novel options to fill …
New antimicrobial hexapeptides: Synthesis, antimicrobial activities, cytotoxicity, and mechanistic studies
Synthetic antimicrobial peptides have recently emerged as promising candidates against
drug‐resistant pathogens. We identified a novel hexapeptide, Orn‐d‐Trp‐d‐Phe‐Ile‐d‐Phe …
drug‐resistant pathogens. We identified a novel hexapeptide, Orn‐d‐Trp‐d‐Phe‐Ile‐d‐Phe …
In pursuit of next-generation therapeutics: Antimicrobial peptides against superbugs, their sources, mechanism of action, nanotechnology-based delivery, and clinical …
A Thakur, A Sharma, HK Alajangi, PK Jaiswal… - International Journal of …, 2022 - Elsevier
Antimicrobial peptides (AMPs) attracted attention as potential source of novel antimicrobials.
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …
Archetypal tryptophan-rich antimicrobial peptides: properties and applications
Abstract Drug-resistant microorganisms ('superbugs') present a serious challenge to the
success of antimicrobial treatments. Subsequently, there is a crucial need for novel bio …
success of antimicrobial treatments. Subsequently, there is a crucial need for novel bio …
Recent advances in antimicrobial peptide-based therapy
A Mulukutla, R Shreshtha, VK Deb, P Chatterjee… - Bioorganic …, 2024 - Elsevier
Antimicrobial peptides (AMPs) are a group of polypeptide chains that have the property to
target and kill a myriad of microbial organisms including viruses, bacteria, protists, etc. The …
target and kill a myriad of microbial organisms including viruses, bacteria, protists, etc. The …