New antimicrobial hexapeptides: Synthesis, antimicrobial activities, cytotoxicity, and mechanistic studies
Synthetic antimicrobial peptides have recently emerged as promising candidates against
drug‐resistant pathogens. We identified a novel hexapeptide, Orn‐d‐Trp‐d‐Phe‐Ile‐d‐Phe …
drug‐resistant pathogens. We identified a novel hexapeptide, Orn‐d‐Trp‐d‐Phe‐Ile‐d‐Phe …
In pursuit of next-generation therapeutics: Antimicrobial peptides against superbugs, their sources, mechanism of action, nanotechnology-based delivery, and clinical …
A Thakur, A Sharma, HK Alajangi, PK Jaiswal… - International Journal of …, 2022 - Elsevier
Antimicrobial peptides (AMPs) attracted attention as potential source of novel antimicrobials.
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …
Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
Discovery, optimization, and clinical application of natural antimicrobial peptides
Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …
diverse molecules are produced as the first line of defense against pathogens such as …
Antimicrobial peptides: Molecular design, structure-function relationship, and biosynthesis optimization
Y Hao, J Wang, C de la Fuente-Nunez… - Frontiers in …, 2022 - frontiersin.org
The long-term use of antibiotics has accelerated the emergence of antibiotic-resistant
bacteria (ARB). Annual global death due to antibiotic resistance is over 700,000 in 2014, it is …
bacteria (ARB). Annual global death due to antibiotic resistance is over 700,000 in 2014, it is …
[PDF][PDF] Peptide antibiotics developed by mimicking natural antimicrobial peptides
N Unubol, S Selim Cinaroglu, MA Elmas, S Akcelik… - Clin …, 2017 - researchgate.net
Antimicrobial peptides are widely preferred drugs for infectious disease treatment. Inspired
from natural antimicrobial peptides, short peptides showing good antibacterial activity are …
from natural antimicrobial peptides, short peptides showing good antibacterial activity are …
Spotlight on the selected new antimicrobial innate immune peptides discovered during 2015-2019
X Dang, G Wang - Current topics in medicinal chemistry, 2020 - ingentaconnect.com
Background: Antibiotic resistance is a global issue and new anti-microbials are required.
Introduction: Anti-microbial peptides are important players of host innate immune systems …
Introduction: Anti-microbial peptides are important players of host innate immune systems …
Archetypal tryptophan-rich antimicrobial peptides: properties and applications
Abstract Drug-resistant microorganisms ('superbugs') present a serious challenge to the
success of antimicrobial treatments. Subsequently, there is a crucial need for novel bio …
success of antimicrobial treatments. Subsequently, there is a crucial need for novel bio …
Recent advances in antimicrobial peptide-based therapy
A Mulukutla, R Shreshtha, VK Deb, P Chatterjee… - Bioorganic …, 2024 - Elsevier
Antimicrobial peptides (AMPs) are a group of polypeptide chains that have the property to
target and kill a myriad of microbial organisms including viruses, bacteria, protists, etc. The …
target and kill a myriad of microbial organisms including viruses, bacteria, protists, etc. The …
Antimicrobial peptide mimics for clinical use: does size matter?
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …