O-dicaffeoyl-3-O-(4-malic acid methylester)–quinic acid (MQA), extracted from Arctium lappa
L., has been observed to exert neuroprotective effects in vitro. The aim of this study was to …

1, 3, 5-Tri-O-caffeoyl quinic acid is a caffeoylquinic acid derivative isolated from the roots of
Arctium lappa L. Our previous studies have revealed that the ethyl acetate extract of the …

Objectives: Compound MQA (1, 5-O-dicaffeoyl-3-O-[4-malic acid methyl ester]-quinic acid) is
a natural caffeoylquinic acid derivative isolated from Arctium lappa L. roots. This study aims …

The effects of caffeic acid phenethyl ester (CAPE), an antioxidant derived from propolis, on
the infarct volume elicited by focal cerebral ischemia were studied on Long–Evans rats …

The aim of the present study was to investigate the protective effect of chicoric acid on
oxidative stress and inflammation in rats with cerebral ischemia‑reperfusion injury. A …

We recently reported the protective effects of chlorogenic acid (CGA) in a transient middle
cerebral artery occlusion (tMCAo) rat model. The current study further investigated the …

Ischemic stroke is a neurovascular disease treatable by thrombolytic therapy, but the therapy
has to be initiated within 3 h of the incident. This therapeutic limitation stems from the …

The present study was conducted to investigate whether caffeic acid phenethyl ester
(CAPE), an active component of propolis extract, has a protective effect on brain injury after …

Cerebral ischemia reperfusion (IR) is associated with neuronal death, which leads to
disability and cognitive decline. The pathomechanism occurs because ischemia is …

Global cerebral ischemia (GCI) is one of the main causes of hippocampal neuronal death.
Ischemic damage can be rescued by early blood reperfusion. However, under some …