The buccal route of administration has a number of advantages including bypassing the
gastrointestinal tract and the hepatic first pass effect. Mucoadhesive films are retentive …

The main route of administration for drug products is the oral route, yet biologics are initially
developed as injectables due to their limited stability through the gastrointestinal tract and …

The potential of the mucoadhesive film technology is hard to ignore, owing to perceived
superior patient acceptability versus buccal tablets, and significant therapeutic opportunities …

Buccal delivery of small and large molecules is an attractive route of administration that has
been studied extensively over the past few decades. This route bypasses first-pass …

Extensive research on transmucosal drug delivery in the past few decades has resulted in
the clinical application of several drug molecules through the buccal route. Interestingly …

Aligned with efforts to overcome shortcomings of conventional oral dosage forms,
mucoadhesive oral thin films have been the focus of drug development. Transmucosal drug …

Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …

ABSTRACT Introduction: According to the European Pharmacopoeia, oromucosal films
comprise mucoadhesive buccal films and orodispersible films. Both oral dosage forms …

Oral drug delivery is the most common route of drug administration. Nevertheless, there are
some important limitations that reinforce the need for developing new drug delivery systems …

Bioadhesive buccal films are innovative dosage forms with the ability to adhere to the
mucosal surface and subsequently hydrate to release and deliver drugs across the buccal …