Cell growth is referred to as cell proliferation, that is, the increase in cell numbers during
repeated cell division. Cell growth can be defined as the enlargement of cell volume, which …

In this paper, we focused on commonly used in vitro assays for estimation of cell death:
morphological analyses of cell death, cytotoxic assays based on enzymes activity …

Cell Proliferation and Apoptosis provides a detailed practical guide to cell proliferation and
apoptosis detection methods. A novel approach combining both these areas allows …

There are several methods to detect apoptosis using cleaved caspase-3 and each harbors
its own advantages and disadvantages. When primary cell cultures are used, the …

In the process of defining the phenotype of a cell, one of the most frequent parameters
scientists measure is the rate of proliferation. Often, the first decision that confronts us is that …

Cells can die either by apoptosis, necrosis or by a form of cell death that displays
morphologic characteristics of both forms (Los et al., 2002; Proskuryakov et al, 2002; …

Joe Clayton, Ph. D. roliferation assays provide quantitative evaluation of a cell population's
viability and growth, and are a crucial aspect of cancer biology research. There are various …

The proliferative activity of a tissue is a direct result of the stimulatory and inhibitory growth
signals received by the cells which compose it. In cancers these messages come from …

When and why do cells die? Does the concentration of environmental pollutants exert
cytotoxic or cytostatic effects on cells? What factors influence the rate and timing of cell …

Differential killing of the patient's cancer cells versus normal cells is a necessity for
chemotherapy. Advantage can be taken of close regulations of gene expression and of …