Pragmatic trials in long-term care: research challenges and potential solutions in relation to key areas of care

B Resnick, S Zimmerman, J Gaugler… - Journal of the American …, 2022 - Elsevier
As a method of research, pragmatic trials are recommended so as to generate results that
are applicable to real-world care. This intent is especially important for the millions of older …

Pragmatic trials in long-term care: Challenges, opportunities, recommendations

C Levy, S Zimmerman, V Mor, D Gifford, SA Greenberg… - Geriatric Nursing, 2022 - Elsevier
Randomized controlled trials are considered the most rigorous research design in efficacy
and effectiveness research; however, such trials present numerous challenges that limit their …

Pragmatic trials in long-term care: Implementation and dissemination challenges and opportunities

C Levy, S Zimmerman, V Mor, D Gifford… - Journal of the American …, 2022 - Elsevier
Randomized controlled trials are considered the most rigorous research design in efficacy
and effectiveness research; however, such trials present numerous challenges that limit their …

[PDF][PDF] Pragmatic trials and improving long-term care: Recommendations from a national institutes of health conference

S Zimmerman, B Resnick, J Ouslander, C Levy… - Geriatric Nursing, 2022 - Elsevier
Email address: JAMDA. Editors@ paltc. org (S. Zimmerman). 22 This work was supported by
the National Institute on Aging (NIA), of the National Institutes 23 of Health, United States …

Statistical considerations for embedded pragmatic clinical trials in people living with dementia

HG Allore, KS Goldfeld, R Gutman, F Li… - Journal of the …, 2020 - Wiley Online Library
There is overwhelming need for nonpharmacological interventions to improve the health
and well‐being of people living with dementia (PLWD). The National Institute on Aging …

Protecting seriously ill populations during pragmatic clinical trials

JM Teno, LC Hanson, JC Lima… - Journal of the American …, 2023 - Wiley Online Library
Pragmatic clinical trials (PCTs) emphasize real‐world effectiveness methodology to address
the limitations of results from explanatory randomized clinical trials (RCTs), which often fail …

Building a national program for pilot studies of embedded pragmatic clinical trials in dementia care

AA Brody, DE Barnes, J Chodosh… - Journal of the …, 2020 - Wiley Online Library
Sixteen million caregivers currently provide care to more than 5 million persons living with
dementia (PLWD) in the United States. Although this population is growing and highly …

Embedded pragmatic trials in dementia care: realizing the vision of the NIA IMPACT Collaboratory

SL Mitchell, V Mor, J Harrison… - Journal of the American …, 2020 - Wiley Online Library
Close to 6 million Americans have Alzheimer's disease (AD) or Alzheimer's disease and
related dementia (AD/ADRD). These high‐need, high‐cost patients are vulnerable to …

Pragmatic trials

I Ford, J Norrie - New England journal of medicine, 2016 - Mass Medical Soc
In pragmatic trials, participants are broadly representative of people who will receive a
treatment or diagnostic strategy, and the outcomes affect day-to-day care. The authors …

Research methods priorities in geriatric palliative medicine

MD Aldridge Carlson - Journal of Palliative Medicine, 2013 - liebertpub.com
Continuing the momentum of geriatric palliative medicine research achieved during the past
decade requires a focus on research methods priorities that span the continuum of research …