Serotonergic neurotransmission in the dorsal raphe nucleus recruits in situ 5-HT2A/2C receptors to modulate the post-ictal antinociception

RL Freitas, GS Bassi, AM de Oliveira… - Experimental neurology, 2008 - Elsevier
The post-ictal immobility syndrome is followed by a significant increase in the nociceptive
thresholds in animals and humans. The aim of this study was to assess the involvement of …

5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus

RL Freitas, CM dos Reis Ferreira, MAC Urbina… - Experimental …, 2009 - Elsevier
Pharmacological studies have been focused on the involvement of different neural pathways
in the organization of antinociception that follows tonic-clonic seizures, including 5 …

Involvement of 5-HT2 serotonergic receptors of the nucleus raphe magnus and nucleus reticularis gigantocellularis/paragigantocellularis complex neural networks in …

RC de Oliveira, R de Oliveira… - Experimental …, 2006 - Elsevier
The post-ictal immobility syndrome is followed by a significant increase in the nociceptive
thresholds in animals and men. In this interesting post-ictal behavioral response …

[HTML][HTML] Acetylcholine-mediated neurotransmission within the nucleus raphe magnus exerts a key role in the organization of both interictal and postictal …

RC de Oliveira, R de Oliveira, PC Zanandréa… - Epilepsy & Behavior, 2011 - Elsevier
The role of the acetylcholine-mediated system in the organization of postictal antinociception
was investigated. For this purpose, nicotinic and muscarinic cholinergic receptor antagonists …

Dorsal raphe nucleus 5-Hydroxytryptamine 2A receptors are critical for the organisation of panic attack-like defensive behaviour and unconditioned fear-induced …

R da Silva Soares Jr, LL Falconi-Sobrinho… - European …, 2019 - Elsevier
Microinjections of N-methyl-d-aspartic acid (NMDA) in the midbrain tectum structures
produce panic attack-like defensive behaviours, followed by an antinociceptive response. It …

5-Hydroxytryptamine 2A receptors of the dorsal raphe nucleus modulate panic-like behaviours and mediate fear-induced antinociception elicited by neuronal …

R da Silva Soares Jr, LL Falconi-Sobrinho… - Behavioural Brain …, 2019 - Elsevier
It has been established that chemical stimulation of the inferior colliculus (IC) of laboratory
animals evokes fear-related defensive responses, which are considered panic attack-like …

5-Hydroxytryptamine2A/2C receptors of nucleus raphe magnus and gigantocellularis/paragigantocellularis pars α reticular nuclei modulate the unconditioned fear …

R de Oliveira, RC de Oliveira… - Behavioural Brain …, 2017 - Elsevier
The electrical stimulation of the dorsolateral columns of the periaquedutal grey matter
(dlPAG) or deep layers of the superior colliculus (dlSC) evokes defensive behaviours …

Serotonergic neural links from the dorsal raphe nucleus modulate defensive behaviours organised by the dorsomedial hypothalamus and the elaboration of fear …

AF Biagioni, RL de Freitas, JA da Silva… - …, 2013 - Elsevier
Decrease of γ-aminobutyric acid (GABA)-mediated neurotransmission in the dorsomedial
hypothalamus (DMH) evokes instinctive fear-like responses. The aim of the present study …

The role of dorsomedial and ventrolateral columns of the periaqueductal gray matter and in situ 5‐HT2A and 5‐HT2C serotonergic receptors in post‐ictal …

RL de Freitas, RC de Oliveira, R de Oliveira… - Synapse, 2014 - Wiley Online Library
The periaqueductal gray matter (PAG) consists in a brainstem structure rich in 5‐
hydroxytryptamine (5‐HT) inputs related to the modulation of pain. The involvement of each …

Serotonergic and nonserotonergic dorsal raphe neurons are pharmacologically and electrophysiologically heterogeneous

S Marinelli, SA Schnell, SP Hack… - Journal of …, 2004 - journals.physiology.org
The dorsal raphe nucleus (DRN) projects serotonergic axons throughout the brain and is
involved in a variety of physiological functions. However, it also includes a large population …