Mechanisms of 5‐HT1A receptor‐mediated transmission in dorsal raphe serotonin neurons

NA Courtney, CP Ford - The Journal of physiology, 2016 - Wiley Online Library
Key points In the dorsal raphe nucleus, it is known that serotonin release activates
metabotropic 5‐HT1A autoreceptors located on serotonin neurons that leads to an inhibition …

GABAergic modulation mediates antinociception produced by serotonin applied into thalamic nucleus submedius of the rat

DQ Xiao, JX Zhu, JS Tang, H Jia - Brain research, 2005 - Elsevier
Our previous studies have indicated that the thalamic nucleus submedius (Sm) is involved in
modulation of nociception as part of an ascending component of an endogenous analgesic …

[HTML][HTML] Paradoxical effect of noradrenaline-mediated neurotransmission in the antinociceptive phenomenon that accompanies tonic–clonic seizures: Role of locus …

TT Felippotti, CM dos Reis Ferreira, RL de Freitas… - Epilepsy & Behavior, 2011 - Elsevier
The postictal state is generally followed by antinociception. It is known that connections
between the dorsal raphe nucleus, the periaqueductal gray matter, and the locus coeruleus …

Interactions of descending serotonergic systems with other neurotransmitters in the modulation of nociception

J Sawynok, A Reid - Behavioural brain research, 1995 - Elsevier
The effects of 5-hydroxytryptamine (5-HT) and ligands selective for particular 5-HT receptor
subtypes on the transmission of nociceptive information in the spinal cord are complex. In …

Serotonin neuronal release from dorsal hippocampus following electrical stimulation of the dorsal and median raphe nuclei in conscious rats

DJ Mokler, D Lariviere, DW Johnson… - …, 1998 - Wiley Online Library
Abstract We have studied 5‐hydroxytryptamine (5‐HT) release in the hippocampal formation
following electrical stimulation of the dorsal and median raphé nuclei in the behaving rat …

Involvement of pre-and post-synaptic serotonergic receptors of dorsal raphe nucleus neural network in the control of the sweet-substance-induced analgesia in adult …

CI Miyase, R Kishi, RL de Freitas, DA Paz… - Neuroscience …, 2005 - Elsevier
In order to investigate the effects of monoaminergic mechanisms of the dorsal raphe nucleus
on the elaboration and control of sweet-substance-induced antinociception, male albino …

An ascending serotonergic pain modulation pathway from the dorsal raphe nucleus to the parafascicularis nucleus of the thalamus

E Andersen, N Dafny - Brain Research, 1983 - Elsevier
Three types of spontaneously active neurons were found in the parafascicularis (PF)
nucleus of the thalamus of the rat: slow firing units (0.5–10 spikes/s), bursting units (2–5 …

[HTML][HTML] Serotonin 5-HT2 receptors activate local GABA inhibitory inputs to serotonergic neurons of the dorsal raphe nucleus

R Liu, T Jolas, G Aghajanian - Brain research, 2000 - Elsevier
The purpose of the present study was to characterize the synaptic currents induced by bath-
applied serotonin (5-HT) in 5-HT cells of the dorsal raphe nucleus (DRN) and to determine …

Electrophysical properties, synaptic transmission and neuromodulation in serotonergic caudal raphe neurons

YW Li, DA Bayliss - Clinical and experimental pharmacology …, 1998 - Wiley Online Library
We studied electrophysiological properties, synaptic transmission and modulation by 5‐
hydroxytryptamine (5‐HT) of caudal raphe neurons using whole‐cell recording in a neonatal …

Differential mediation of descending pain facilitation and inhibition by spinal 5HT-3 and 5HT-7 receptors

A Dogrul, MH Ossipov, F Porreca - Brain research, 2009 - Elsevier
The rostroventromedial medulla (RVM) is an important source of descending modulatory
systems that both inhibit and facilitate pain at the level of the spinal cord. Noxious stimuli can …