PLA2R antibodies, glomerular PLA2R deposits and variations in PLA2R1 and HLA-DQA1 genes in primary membranous nephropathy in South Asians

R Ramachandran, V Kumar, A Kumar… - Nephrology Dialysis …, 2016 - academic.oup.com
Background Antibodies to M-type phospholipase A2 receptor (PLA2R) correlate with clinical
activity of primary membranous nephropathy (PMN). Risk alleles in PLA2R1 and HLA-DQA1 …

[HTML][HTML] Anti-PLA2R antibodies measured by ELISA predict long-term outcome in a prevalent population of patients with idiopathic membranous nephropathy

D Kanigicherla, J Gummadova, EA McKenzie… - Kidney international, 2013 - Elsevier
Antibodies to the phospholipase A2 receptor 1 (PLA2R1) have been reported in 70% of
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …

Analysis of PLA2R1 and HLA-DQA1 sequence variants in Japanese patients with idiopathic and secondary membranous nephropathy

H Kaga, A Komatsuda, A Omokawa, S Okuyama… - Clinical and …, 2018 - Springer
Background Several recent studies in patients with idiopathic membranous nephropathy
(iMN) from Western and Asian counties showed that some single nucleotide polymorphisms …

Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy

MJH Coenen, JM Hofstra, H Debiec… - Journal of the …, 2013 - journals.lww.com
The M-type receptor for phospholipase A2 (PLA2R1) is the major target antigen in idiopathic
membranous nephropathy (iMN). Our recent genome-wide association study showed that …

Single Nucleotide Polymorphisms in the Phospholipase A2 Receptor Gene Are Associated with Genetic Susceptibility to Idiopathic Membranous Nephropathy

S Kim, HJ Chin, KY Na, S Kim, J Oh, W Chung… - Nephron Clinical …, 2011 - karger.com
Background: The phospholipase A2 receptor (PLA2R) is a major antigen found in patients
with idiopathic membranous nephropathy (MN). The relationship of genetic polymorphisms …

PLA2R and membranous nephropathy: a 3 year prospective Australian study

PA Hill, JL McRae, KM Dwyer - Nephrology, 2016 - Wiley Online Library
Aim The phospholipase A2 receptor (PLA2R) is the major target antigen in idiopathic
membranous nephropathy (iMN). The aim of this prospective study was to determine the …

Interaction between PLA2R1 and HLA-DQA1 variants associates with anti-PLA2R antibodies and membranous nephropathy

J Lv, W Hou, X Zhou, G Liu, F Zhou… - Journal of the …, 2013 - journals.lww.com
Risk alleles at genome loci containing phospholipase A2 receptor 1 (PLA2R1) and HLA-
DQA1 closely associate with idiopathic membranous nephropathy (IMN) in the European …

[HTML][HTML] Serum anti-PLA2R antibody and glomerular PLA2R deposition in Chinese patients with membranous nephropathy: a cross-sectional study

L Pang, AM Zhang, HX Li, JL Du, LL Jiao, N Duan… - Medicine, 2017 - journals.lww.com
M-type phospholipase A2 receptor (PLA2R) is the major target antigen in primary
membranous nephropathy (PMN). Previous studies have evaluated the diagnostic value of …

Genetics of membranous nephropathy

S Gupta, A Köttgen, E Hoxha… - Nephrology Dialysis …, 2018 - academic.oup.com
An HLA-DR3 association with membranous nephropathy (MN) was described in 1979 and
additional evidence for a genetic component to MN was suggested in 1984 in reports of …

Clinicopathological characteristics of M-type phospholipase A2 receptor (PLA2R)-related membranous nephropathy in Japanese

N Hayashi, S Akiyama, H Okuyama, Y Matsui… - Clinical and …, 2015 - Springer
Background Recent studies have suggested that assessments of serum antibodies against
M-type phospholipase A2 receptor (PLA2R) and the glomerular expression of PLA2R …