Human placental mesenchymal stem cells of fetal origins-alleviated inflammation and fibrosis by attenuating MyD88 signaling in bleomycin-induced pulmonary …

F Li, F Han, H Li, J Zhang, X Qiao, J Shi, L Yang… - Molecular …, 2017 - Elsevier
Pulmonary fibrosis is a progressive lung disease that its pathogenic mechanism currently is
incompletely understood. Toll-like receptor (TLR) signaling has recently been identified as a …

Amniotic MSCs reduce pulmonary fibrosis by hampering lung B-cell recruitment, retention, and maturation

A Cargnoni, P Romele… - Stem cells …, 2020 - academic.oup.com
Growing evidence suggests a mechanistic link between inflammation and the development
and progression of fibrotic processes. Mesenchymal stromal cells derived from the human …

Human umbilical cord mesenchymal stromal cells attenuate pulmonary fibrosis via regulatory T cell through interaction with macrophage

Z Tang, J Gao, J Wu, G Zeng, Y Liao, Z Song… - Stem Cell Research & …, 2021 - Springer
Background Pulmonary fibrosis (PF) is a growing clinical problem with limited therapeutic
options. Human umbilical cord mesenchymal stromal cell (hucMSC) therapy is being …

Classical monocyte-derived macrophages as therapeutic targets of umbilical cord mesenchymal stem cells: comparison of intratracheal and intravenous …

SM Choi, Y Mo, JY Bang, YG Ko, YH Ahn, HY Kim… - Respiratory …, 2023 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease that
has no cure. Although mesenchymal stem cells (MSCs) have been reported to ameliorate …

Human menstrual blood-derived stem cells mitigate bleomycin-induced pulmonary fibrosis through anti-apoptosis and anti-inflammatory effects

X Chen, Y Wu, Y Wang, L Chen, W Zheng… - Stem Cell Research & …, 2020 - Springer
Background Idiopathic pulmonary fibrosis is a kind of diffuse interstitial lung disease, the
pathogenesis of which is unclear, and there is currently a lack of good treatment to improve …

[HTML][HTML] Promising Therapeutic Effects of Embryonic Stem Cells-Origin Mesenchymal Stem Cells in Experimental Pulmonary Fibrosis Models: Immunomodulatory and …

H Lee, OY Jeong, HJ Park, SL Lee, E Bok, M Kim… - Immune …, 2023 - ncbi.nlm.nih.gov
Interstitial lung disease (ILD) involves persistent inflammation and fibrosis, leading to
respiratory failure and even death. Adult tissue-derived mesenchymal stem cells (MSCs) …

Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis

M Liu, X Zeng, J Wang, Z Fu, J Wang, M Liu… - Stem cell research & …, 2016 - Springer
Background Interstitial pneumonia in connective tissue diseases (CTD-IP) featuring
inflammation and fibrosis is a leading cause of death in CTD-IP patients. The related …

M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis

J Hou, J Shi, L Chen, Z Lv, X Chen, H Cao… - Cell Communication and …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by
the histopathological pattern of usual interstitial pneumonia and is associated with a high …

PD-1/PD-L1 pathway mediates the alleviation of pulmonary fibrosis by human mesenchymal stem cells in humanized mice

K Ni, M Liu, J Zheng, L Wen, Q Chen… - American Journal of …, 2018 - atsjournals.org
Pulmonary fibrosis is a chronic progressive lung disease with few treatments. Human
mesenchymal stem cells (MSCs) have been shown to be beneficial in pulmonary fibrosis …

Transplantation of human placenta mesenchymal stem cells reduces the level of inflammatory factors in lung tissues of mice with acute lung injury

M Xu, G Liu, Y Jia, X Yan, X Ma, J Wei… - Xi bao yu fen zi Mian yi …, 2018 - europepmc.org
Objective To investigate the influence of human placenta mesenchymal stem cells
(hPMSCs) on the expression levels of inflammatory factors in the lung tissues of …