Amyotrophic lateral sclerosis: a focus on disease progression
AC Calvo, R Manzano, DMF Mendonça… - BioMed research …, 2014 - Wiley Online Library
Since amyotrophic lateral sclerosis (ALS) was discovered and described in 1869 as a
neurodegenerative disease in which motor neuron death is induced, a wide range of …
neurodegenerative disease in which motor neuron death is induced, a wide range of …
Biomarkers in amyotrophic lateral sclerosis: opportunities and limitations
Insights into the mechanisms of amyotrophic lateral sclerosis (ALS) have relied
predominantly on the study of postmortem tissue. Modern technology has improved the …
predominantly on the study of postmortem tissue. Modern technology has improved the …
Current view and perspectives in amyotrophic lateral sclerosis
S Mathis, P Couratier, A Julian, P Corcia… - Neural Regeneration …, 2017 - journals.lww.com
Amyotrophic lateral sclerosis (ALS), identified as a distinct clinical entity by Charcot since the
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …
Epigenetic mechanisms of gene regulation in amyotrophic lateral sclerosis
Despite being clinically described 150 years ago, the mechanisms underlying amyotrophic
lateral sclerosis (ALS) pathogenesis have not yet been fully understood. Studies in both …
lateral sclerosis (ALS) pathogenesis have not yet been fully understood. Studies in both …
The 'omics' of amyotrophic lateral sclerosis
D Caballero-Hernandez, MG Toscano… - Trends in molecular …, 2016 - cell.com
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease that primarily
affects motor neurons and is accompanied by sustained unregulated immune responses …
affects motor neurons and is accompanied by sustained unregulated immune responses …
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …
motor neurons. As with all major neurodegenerative disorders, development of disease …
Amyotrophic lateral sclerosis–looking for pathogenesis and effective therapy
E Naganska, E Matyja - Folia Neuropathologica, 2011 - termedia.pl
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which …
characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which …
New therapeutic targets for amyotrophic lateral sclerosis
M Kuzma-Kozakiewicz, H Kwiecinski - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological
disorders, affecting approximately half a million people worldwide. Currently there is no cure …
disorders, affecting approximately half a million people worldwide. Currently there is no cure …
Amyotrophic lateral sclerosis: contemporary concepts in etiopathogenesis and pharmacotherapy
MJ Strong - Expert opinion on investigational drugs, 2004 - Taylor & Francis
Among the neurodegenerative diseases associated with ageing, amyotrophic lateral
sclerosis (ALS) remains the most devastating. The disease inexorably progresses, the vast …
sclerosis (ALS) remains the most devastating. The disease inexorably progresses, the vast …
[PDF][PDF] Transcriptomics in amyotrophic lateral sclerosis
MG Krokidis, P Vlamos - Front Biosci (Elite Ed), 2018 - article.imrpress.com
Amyotrophic lateral sclerosis (ALS) is an adult-onset, incurable neurodegenerative disease
characterized by the selective death of upper and lowers motor neurons in the spinal cord …
characterized by the selective death of upper and lowers motor neurons in the spinal cord …