Since amyotrophic lateral sclerosis (ALS) was discovered and described in 1869 as a
neurodegenerative disease in which motor neuron death is induced, a wide range of …

Insights into the mechanisms of amyotrophic lateral sclerosis (ALS) have relied
predominantly on the study of postmortem tissue. Modern technology has improved the …

Amyotrophic lateral sclerosis (ALS), identified as a distinct clinical entity by Charcot since the
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …

Despite being clinically described 150 years ago, the mechanisms underlying amyotrophic
lateral sclerosis (ALS) pathogenesis have not yet been fully understood. Studies in both …

Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease that primarily
affects motor neurons and is accompanied by sustained unregulated immune responses …

Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which …

Introduction: Amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological
disorders, affecting approximately half a million people worldwide. Currently there is no cure …

Among the neurodegenerative diseases associated with ageing, amyotrophic lateral
sclerosis (ALS) remains the most devastating. The disease inexorably progresses, the vast …

Amyotrophic lateral sclerosis (ALS) is an adult-onset, incurable neurodegenerative disease
characterized by the selective death of upper and lowers motor neurons in the spinal cord …