Current trends and future prospects of molecular targeted therapy in head and neck squamous cell carcinoma

N Kitamura, S Sento, Y Yoshizawa, E Sasabe… - International journal of …, 2020 - mdpi.com
In recent years, advances in drug therapy for head and neck squamous cell carcinoma
(HNSCC) have progressed rapidly. In addition to cytotoxic anti-cancer agents such as …

Targeted therapy for head and neck cancer: signaling pathways and clinical studies

Q Li, Y Tie, A Alu, X Ma, H Shi - Signal transduction and targeted …, 2023 - nature.com
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …

Application of molecular targeted therapies in the treatment of head and neck squamous cell carcinoma

P Kozakiewicz… - Oncology …, 2018 - spandidos-publications.com
Despite the development of standard therapies, including surgery, radiotherapy and
chemotherapy, survival rates for head and neck squamous cell carcinoma (HNSCC) have …

Recent advances and future directions in clinical management of head and neck squamous cell carcinoma

J Muzaffar, S Bari, K Kirtane, CH Chung - Cancers, 2021 - mdpi.com
Simple Summary Even with recent advances, there are urgent needs for novel therapies to
improve overall survival and decrease toxicities in the management of head and neck …

Immunotherapies and future combination strategies for head and neck squamous cell carcinoma

V Cristina, RG Herrera-Gómez, P Szturz… - International journal of …, 2019 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is often diagnosed at an advanced
stage and has a dismal prognosis. Nearly 10 years after the approval of cetuximab, anti …

Novel systemic treatment modalities including immunotherapy and molecular targeted therapy for recurrent and metastatic head and neck squamous cell carcinoma

S Ghosh, PA Shah, FM Johnson - International journal of molecular …, 2022 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common cancers
worldwide. More than half of patients with HNSCC eventually experience disease …

[HTML][HTML] Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials

B Goel, AK Tiwari, RK Pandey, AP Singh, S Kumar… - Translational …, 2022 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …

Emerging drugs to treat squamous cell carcinomas of the head and neck

C Fung, JR Grandis - Expert opinion on emerging drugs, 2010 - Taylor & Francis
Importance of the field: Head and neck squamous cell carcinoma (HNSCC) is the eighth
leading cause of cancer death worldwide. Despite advances in surgery and chemoradiation …

Promising new molecular targeted therapies in head and neck cancer

K Dorsey, M Agulnik - Drugs, 2013 - Springer
Despite advances in multimodality therapies for the treatment of squamous cell carcinoma of
the head and neck (SCCHN), survival rates, functional outcomes and toxicities of therapy …

Targeted therapies for squamous cell carcinoma of the head and neck: current knowledge and future directions

S Schmitz, KK Ang, J Vermorken, R Haddad… - Cancer treatment …, 2014 - Elsevier
Despite progress in the therapeutic management of patients with squamous cell carcinoma
of the head and neck (SCCHN), the mortality rate of patients presenting with advanced …