Abstract Treatment effectiveness for kidney disease is limited by lack of accuracy, sensitivity,
specificity of diagnostic, prognostic, and therapeutic biomarkers. The gold standard test …

Proteomics-based approaches are generating considerable data in clinical nephrology
covering almost all aspects of the discipline. Proteomic experiments commonly involve …

BACKGROUND Technological advances have resulted in a renaissance of proteomic
studies directed at finding markers of disease progression, diagnosis, or responsiveness to …

Nephrotic syndrome is not a single disease; rather, it is a term for numerous diseases and
pathological types. Renal biopsy is of use in determining the diagnosis and prognosis, and …

Biomarkers have the potential to greatly facilitate diagnosis and treatment of patients with
various forms of kidney disease. State-of-the-art mass spectrometry-based methods possess …

The kidney glomerulus is the site of plasma filtration and production of primary urine in the
kidney. The structure not only plays a pivotal role in ultrafiltration of plasma into urine but …

Noninvasive diagnosis of kidney diseases and assessment of the prognosis are still
challenges in clinical nephrology. Definition of biomarkers on the basis of proteome …

The novel discipline of proteomics has experienced a rapid growth in the recent past and
has a great potential for the future. Involving several fields, it offers various advantages: The …

An increasing number of patients suffering from renal diseases and limitations in standard
diagnostic and therapeutic approaches has created an intense interest in applying …

Chronic kidney disease (CKD) is a non-specific type of kidney disease that causes a gradual
decline in kidney function (from months to years). CKD is a significant risk factor for death …