Background The contrast between a high prevalence of chronic kidney disease (CKD) and
the low incidence of end-stage renal disease highlights the need for new biomarkers of …

Biomarkers hold the promise of significantly improving health care by enabling prognosis
and diagnosis with improved accuracy, and at earlier points in time. Previous results have …

Background: Discovery of the ideal biomarker for clinical care remains a major challenge.
Recent progress in genomic and proteomic technologies has allowed the identification of …

Kidney research is entering an era of 'big data'and molecular omics data can provide
comprehensive insights into the molecular footprints of cells. In contrast to transcriptomics …

Glomerular diseases are often chronic or recurring and thus associated with a tremendous
physical, psychological, and economic burden. Their etiologies are often unknown, and their …

Purpose: The poor performance of current tests for predicting the onset, progression and
treatment response of diabetic nephropathy has engendered a search for more sensitive …

Mass spectrometry (MS) was introduced into clinical laboratories, and first applied to the
evaluation of children at risk of inborn errors of metabolism. For the analysis of …

Kidney disease is one of the fastest growing causes of death worldwide, disclosing an
unmet clinical need for early diagnosis and optimized risk stratification that allows high risk …

Proteome analysis has emerged as a new field of protein science offering the possibility of
achieving unbiased identification, quantification and functional assessment of all proteins …

At present time, clinical practice requires advanced studies of plasma and urinary
proteomics which should allow the identification, selection, and implementation of plasma …