The strong need for the discovery of novel disease markers together with the development of
high-throughput techniques that provide highly sensitive analysis of protein content in …

Urinary proteomic biomarkers have emerged as clinically relevant variables. First studies
involving several hundred individuals indicate a potential added benefit of urinary proteomic …

Traditional biomarkers of renal disease have a number of limitations, whether evaluating
veterinary patients or performing preclinical toxicity studies. Serum creatinine and urea …

During the past few years, proteomics has been extensively applied to various fields of
medicine including nephrology. Current applications of renal and urinary proteomics are to …

Cancer is a big problem in the developed world as well as in developing countries. Renal
cell carcinoma (RCC) accounts for approximately 3% of adult malignancies and 90–95% of …

The increasing number of patients suffering from chronic renal failure represents one of the
major challenges which the nephrologists are facing worldwide. For a better therapeutic …

Diagnosis of the type of glomerular disease that causes the nephrotic syndrome is
necessary for appropriate treatment and typically requires a renal biopsy. The goal of this …

Proteomics has long been considered an ideal platform, and urine an ideal source for
biomarker discovery in human autoimmune kidney diseases. A number of studies have …

Purpose Idiopathic nephrotic syndrome (NS) is characterized by proteinuria, edema, and
hypoalbuminemia. The aim of the study was to identify differentially expressed proteins in …

The last decade has seen a surge in publications describing novel biomarkers for early
detection of diabetic nephropathy (DN), but as yet none have outperformed albuminuria in …