Changing the concepts of immune‐mediated glomerular diseases through proteomics

DJ Caster, L Hobeika, JB Klein… - PROTEOMICS …, 2015 - Wiley Online Library
Standard classification of glomerular diseases is based on histopathologic abnormalities.
The recent application of proteomic technologies has resulted in paradigm changes in the …

Application of proteomic analysis to renal disease in the clinic

BA Julian, H Suzuki, G Spasovski… - PROTEOMICS …, 2009 - Wiley Online Library
Chronic kidney disease accounts for a significant portion of many national health‐care
budgets. In this viewpoint, we highlight recent advances in urinary proteomic analyses that …

[HTML][HTML] Urinary and plasma proteomics to discover biomarkers for diagnosing between diabetic nephropathy and minimal change nephrotic syndrome or …

A Araumi, T Osaki, K Ichikawa, K Kudo, N Suzuki… - … and biophysics reports, 2021 - Elsevier
The choice of treatment for primary nephrotic syndrome depends on the pathologic type of
the disorder. Renal biopsy is necessary for a definitive diagnosis, but it is burdensome for …

Insights into predicting diabetic nephropathy using urinary biomarkers

NU Khan, J Lin, X Liu, H Li, W Lu, Z Zhong… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Diabetic nephropathy (DN) is a serious complication of diabetes caused by changes in the
structure and function of the kidneys. It is important to detect diagnostic biomarkers of DN at …

[HTML][HTML] Applying proteomics to diagnosis of diabetic kidney disease

RN Moresco, JAM De Carvalho - Expert review of proteomics, 2017 - Taylor & Francis
Diabetic kidney disease (DKD) is one the major complications of diabetes and has become
the most common cause of chronic kidney disease worldwide [1, 2]. The pathogenesis of …

Urinary proteomics and precision medicine for chronic kidney disease: current status and future perspectives

F Persson, P Rossing - PROTEOMICS–Clinical Applications, 2019 - Wiley Online Library
Precision medicine is since long an ongoing refinement of classical medicine, integrating
improved and more detailed pathophysiological understanding with rapid technological …

Biochemical markers of renal function

D Krstic, N Tomic, B Radosavljevic… - Current medicinal …, 2016 - ingentaconnect.com
Kidney damage can be induced by ischemia, autoimmune diseases, hypertension, allograft
rejection, metabolic or genetic disorders, infections or toxins. The influence of these factors …

[HTML][HTML] Biomarkers in progressive chronic kidney disease. Still a long way to go

T Ntrinias, M Papasotiriou, L Balta, D Kalavrizioti… - Prilozi, 2019 - sciendo.com
The traditional chronic kidney disease (CKD) biomarkers (eGFR based on serum creatinine,
sex and age and albuminuria) cannot predict a patient's individual risk for developing …

Diabetic nephropathy: traditional to proteomic markers

RN Moresco, MB Sangoi, JAM De Carvalho, E Tatsch… - Clinica chimica acta, 2013 - Elsevier
Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes and
it is defined as a rise in the urinary albumin excretion (UAE) rate and abnormal renal …

Urinary proteome in a snapshot: normal urine and glomerulonephritis.

L Santucci, G Candiano, M Bruschi, M Bodria… - Journal of …, 2012 - europepmc.org
The analysis of the urinary proteome is a potential source of information regarding the
kidney's physiopathology. A clear knowledge of the protein composition of normal urine is …