THYROID follicular cell tumors present a unique model for the study of genetic and
environmental factors predisposing to benign nodule formation, well differentiated malignant …

A number of molecular abnormalities have been described in association with the
progression from normal thyroid tissue to benign adenomas to well-differentiated and finally …

Cytogenetic and molecular analyses of thyroid tumors have indicated that these neoplasms
represent a good model for analyzing human epithelial cell multistep carcinogenesis. They …

Cancers are thought to develop as a result of sequential mutations of genes important in the
control of cellular growth. Recently investigators identified a number of genetic defects that …

Tumors of thyroid follicular cells provide a very interesting model to understand the
development of human cancer. It is becoming apparent that distinct molecular events are …

Objective: To identify molecular markers useful for the diagnostic discrimination of benign
and malignant follicular thyroid tumors. Methods: A panel of thyroid tumors was …

Thyroid cancer derived from follicular cells is the most common endocrine malignancy. The
past decade has seen progress in our understanding of the pathogenesis of the various …

Neoplasms arise as a result of an accumulation of inherited and/or somatic mutations of
genes involved in the control of cellular growth and/or differentiation. This microevolutionary …

The increased expression or abnormal structure of oncogenes has been implicated in many
types of human tumors, including epithelial and medullary carcinomas of the thyroid. Some …

Tumours of the thyroid follicular cell are proving to be one of the most informative models for
'dissecting'the molecular genetics of multi-stage human tumorigenesis. Early thyroid tumour …