Organophosphorus pesticide degradation product in vitro metabolic stability and time-course uptake and elimination in rats following oral and intravenous dosing

ND Forsberg, R Rodriguez-Proteau, L Ma, J Morré… - Xenobiotica, 2011 - Taylor & Francis
Levels of urinary dialkylphosphates (DAPs) are currently used as a biomarker of human
exposure to organophosphorus insecticides (OPs). It is known that OPs degrade on food …

Determination of dialkyl phosphate metabolites of organophosphorus pesticides in human urine by automated solid-phase extraction, derivatization, and gas …

GKH De Alwis, LL Needham… - Journal of analytical …, 2008 - academic.oup.com
Organophosphorus (OP) pesticides are highly toxic but used commonly worldwide,
nevertheless. Their urinary dialkylphosphate (DAP) metabolites are widely used for …

A mass spectrometry-based method to measure dialkylphosphate degradation products of organophosphorous insecticides in dust and orange juice

G Weerasekera, KD Smith, L Quirós-Alcalá… - Journal of …, 2009 - pubs.rsc.org
Dialkylphosphates (DAPs) are urinary metabolites and breakdown products of
organophosphorous (OP) pesticides. Urinary DAPs are widely used to assess exposure to …

Quantification of dialkylphosphate metabolites of organophosphorus insecticides in human urine using 96-well plate sample preparation and high-performance liquid …

MS Odetokun, MA Montesano, G Weerasekera… - … of Chromatography B, 2010 - Elsevier
Organophosphorus (OP) pesticides kill by disrupting a targeted pest's brain and nervous
systems. But if humans and other animals are sufficiently exposed, OP pesticides can have …

Measurement of dialkyl phosphate metabolites of organophosphorus pesticides in human urine using lyophilization with gas chromatography-tandem mass …

R Bravo, LM Caltabiano, G Weerasekera… - Journal of Exposure …, 2004 - nature.com
Urinary dialkylphosphate (DAP) metabolites have been used to estimate human exposure to
organophosphorus pesticides. We developed a method for quantifying the six DAP urinary …

Revised method for routine determination of urinary dialkyl phosphates using gas chromatography–mass spectrometry

J Ueyama, M Kamijima, T Kondo, K Takagi… - … of Chromatography B, 2010 - Elsevier
Among urinary organophosphorus pesticide (OP) metabolites, dialkyl phosphates (DAPs)
have been most often measured as a sensitive biomarker in non-occupational and …

Dialkylphosphates (DAPs) in fruits and vegetables may confound biomonitoring in organophosphorus insecticide exposure and risk assessment

X Zhang, JH Driver, Y Li, JH Ross… - Journal of agricultural …, 2008 - ACS Publications
Trace residues of organophosphorus (OP) pesticides are associated with fruits and
vegetables that have been sprayed with those OP pesticides to guard against insect pests …

Development of an ion-pair liquid chromatography–high resolution mass spectrometry method for determination of organophosphate pesticide metabolites in large …

E Cequier, AK Sakhi, LS Haug, C Thomsen - Journal of Chromatography A, 2016 - Elsevier
Organophosphate based pesticides are widely used in the agricultural sector, and exposure
to these chemicals is common for the general population. Pesticides are toxic due to the …

Development and Validation of a New UFLC–MS/MS Method for the Detection of Organophosphate Pesticide Metabolites in Urine

D Kumar, SN Sinha, K Vasudev - Molecules, 2023 - mdpi.com
To monitor human exposure to pesticides, experts commonly measure their metabolites in
urine, particularly dialkyl phosphates (DAPs), which include diethyl phosphate (DEP) …

Temporal variability of organophosphate insecticide metabolites over one year in Chinese adults

X Lin, Z Zhang, B Wu, J Liu - Science of The Total Environment, 2021 - Elsevier
Organophosphate (OP) insecticides widely used worldwide are a class of non-persistent
pollutants with a short biological half-life. Most OP insecticides are rapidly metabolized in the …