Most neutralizing antibodies elicited during influenza virus infection or by vaccination have a
narrow spectrum because they usually target variable epitopes in the globular head region …

The epitope sequences within the hemagglutinin (HA) of influenza A virus H3N2 at amino
acid residues 173–181 and 227–239 that forms anti-parallel β-sheet structure are similarly …

Most neutralizing antibodies elicited during influenza virus infection or vaccination target
immunodominant, variable epitopes on the globular head region of hemagglutinin (HA) …

ABSTRACT A human monoclonal heterosubtypic antibody, MAb 3.1, with its heavy chain
encoded by VH3-30, was isolated using phage display with immobilized hemagglutinin (HA) …

The conserved influenza virus hemagglutinin (HA) stem domain elicits cross-reactive
antibodies, but epitopes in the globular head typically elicit strain-specific responses …

Neutralizing antibodies that target the hemagglutinin of influenza virus either inhibit binding
of hemagglutinin to cellular receptors or prevent the low-pH-induced conformational change …

The hemagglutinin protein of H3N2 influenza viruses is the major target of neutralizing
antibodies induced by infection and vaccination. However, the virus frequently escapes …

Influenza A virus infection is a persistent threat to public health worldwide due to its ability to
evade immune surveillance through rapid genetic drift and shift. Current vaccines against …

Due to continuous changes to its antigenic regions, influenza viruses can evade immune
detection and cause a significant amount of morbidity and mortality around the world …

Hemagglutinin (HA), the major antigen on the surface of influenza viruses, is the primary
target for neutralizing antibodies and vaccine design. However, frequent mutations in this …