Although there is increasing interest in the use of oral appliances to treat obstructive sleep
apnea (OSA), the evidence base for this is weak. Furthermore, the precise mechanisms of …

Abstract Treatment of OSA with CPAP is currently the recommended treatment and has the
greatest evidence of efficacy on AHI, symptoms and comorbidities. Symptomatic patients …

Obstructive sleep apnea (OSA) is a chronic disorder and effective long-term treatment is
necessary to prevent associated health risks. Standard treatment remains continuous …

Study Objective: To determine the long-term clinical effectiveness and safety of
maxillomandibular advancement (MMA) for the treatment of moderate to severe obstructive …

Obstructive sleep apnea (OSA) is a complex disorder characterized by collapse of the upper
airway during sleep. Downstream effects involve the cardiovascular, pulmonary, and …

The aim of this study was to evaluate the effect of a mandibular advancement splint (MAS)
on daytime sleepiness and a range of other symptoms in obstructive sleep apnea (OSA) …

Background: Previous randomized controlled trials have addressed the efficacy of
mandibular advancement devices (MADs) in the treatment of obstructive sleep apnea (OSA) …

Importance Many adults with obstructive sleep apnea (OSA) use device treatments
inadequately and remain untreated. Objective To determine whether combined palatal and …

Background We sought to establish the efficacy of an adjustable oral appliance (aOA) in the
largest patient population studied to date, to our knowledge, and to provide a comparison …