Measuring ovarian toxicity in clinical trials: an American Society of Clinical Oncology research statement

W Cui, RP Rocconi, R Thota, RA Anderson… - The Lancet …, 2023 - thelancet.com
Anticancer agents can impair ovarian function, resulting in premature menopause and
associated long-term health effects. Ovarian toxicity is not usually adequately assessed in …

New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential

S Banerjee, SB Kaye - Clinical cancer research, 2013 - AACR
The treatment of ovarian cancer is set to undergo rapid changes, as strategies incorporating
molecular targeted therapies begin to take shape. These are based on a better appreciation …

Molecular targeted therapy in ovarian cancer: what is on the horizon?

R Kalachand, BT Hennessy, M Markman - Drugs, 2011 - Springer
Over the past two decades, empirical optimization of cytotoxic chemotherapy combinations
and surgical debulking procedures have improved outcomes and survival in epithelial …

The efficacy and safety of angiogenesis inhibitors for recurrent ovarian cancer: a meta‑analysis

C Zhang, W Zhao - Journal of Ovarian Research, 2022 - Springer
Objective To investigate the efficacy and safety of angiogenesis inhibitors in the treatment of
recurrent ovarian cancer (OC). Methods Electronic databases including PubMed, Web of …

Clinical trials in ovarian carcinoma: study methodology

JB Vermorken, MKB Parmar, MF Brady… - Annals of oncology, 2005 - Elsevier
One of the major issues in the 3rd Ovarian Cancer Consensus Conference (OCCC) was to
achieve consensus among study groups worldwide on appropriate requirements for entry …

The search for biomarkers to direct antiangiogenic treatment in epithelial ovarian cancer

AA Secord, AB Nixon, HI Hurwitz - Gynecologic oncology, 2014 - Elsevier
Antiangiogenic agents have demonstrated improved progression-free survival in women
with primary and recurrent epithelial ovarian cancer (EOC). Biomarkers that predict …

Bringing new medicines to women with epithelial ovarian cancer: what is the unmet medical need?

TJ Herzog, BJ Monk - Gynecologic oncology research and practice, 2017 - Springer
Background Therapy for advanced epithelial ovarian cancer (OC) includes first line
platinum/taxane-containing chemotherapy and re-treatment with platinum-containing …

Emerging drugs for ovarian cancer

LR Kelland - Expert Opinion on Emerging Drugs, 2005 - Taylor & Francis
Because most patients presenting with advanced ovarian cancer are not curable by surgery
alone, chemotherapy represents an essential component of treatment. The disease may be …

New, expanded, and modified use of approved antineoplastic agents in ovarian cancer

M Markman - The oncologist, 2007 - academic.oup.com
Over the past several years, clinical research efforts in ovarian cancer employing a number
of US Food and Drug Administration (FDA)-approved antineoplastic agents have permitted …

Review of the current role of targeted therapies as maintenance therapies in first and second line treatment of epithelial ovarian cancer; In the light of completed trials

T Korkmaz, S Seber, G Basaran - Critical reviews in oncology/hematology, 2016 - Elsevier
Late and recurrent stage ovarian cancer has a high mortality and low response rate to
therapy beyond first line treatment. Although first line platinum/taxane based regimens have …