Mast cells mediate allergies, hypersensitivities, host defense, and venom neutralization. An
area of recent interest is the contribution of mast cells to inflammatory pain. Here we found …

Through the release of biologically active products, mast cells function as important effector
and immunoregulatory cells in diverse immunological reactions and other biological …

Mast cells (MCs) are tissue resident immune cells that participate in a variety of allergic and
other inflammatory conditions. In most tissues, MCs are found in close proximity to nerve …

Mast cells have long been recognized as potent producers of a large panel of biologically
highly active mediators such as biogenic amines, arachidonic acid metabolites, cytokines …

Mast cells have long been known to play a detrimental role in the pathogenesis of IgE-
associated allergic disorders by their ability to release a wide variety of pro-inflammatory …

Although mast cells have long been known to play a critical role in anaphylaxis and other
allergic diseases, they also participate in some innate immune responses and may even …

Mast cells have been implicated as the central effectors in allergic responses, yet a fatal
anaphylactic response can be induced in mast cell-deficient mice. In this study, we …

Mast cells are important first responders in protective pain responses that provoke
withdrawal from intense, noxious environmental stimuli, in part because of their sentinel …

Antigen‐mediated mast cell activation is a pivotal step in the initiation of allergic disorders
including anaphylaxis and atopy. To date, studies aimed at investigating the mechanisms …

Mast cells are immunological cells that are diversely distributed in different parts of the body.
Their role in various pathological conditions such as hypersensitivity, atherosclerosis …