Action of six pyrethrins purified from the botanical insecticide pyrethrum on cockroach sodium channels expressed in Xenopus oocytes
Pyrethrin I, pyrethrin II, cinerin I, cinerin II, jasmolin I and jasmolin II are six closely related
insecticidal active esters, known as pyrethrins, found in the pyrethrum extract from the dry …
insecticidal active esters, known as pyrethrins, found in the pyrethrum extract from the dry …
Ion channels: molecular targets of neuroactive insecticides
V Raymond-Delpech, K Matsuda, BM Sattelle… - Invertebrate …, 2005 - Springer
Many of the insecticides in current use act on molecular targets in the insect nervous system.
Recently, our understanding of these targets has improved as a result of the complete …
Recently, our understanding of these targets has improved as a result of the complete …
Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding
J Tan, Z Liu, R Wang, ZY Huang, AC Chen… - Molecular …, 2005 - ASPET
The voltage-gated sodium channel is the primary target site of pyrethroids, which constitute
a major class of insecticides used worldwide. Pyrethroids prolong the opening of sodium …
a major class of insecticides used worldwide. Pyrethroids prolong the opening of sodium …
Allethrin differentially modulates voltage-gated calcium channel subtypes in rat PC12 cells
AP Neal, Y Yuan, WD Atchison - Toxicological sciences, 2010 - academic.oup.com
Pyrethroid insecticides are one of the most widely used classes of insecticides. Previous
studies revealed that pyrethroids potently affect the insect voltage-gated sodium (Na+) …
studies revealed that pyrethroids potently affect the insect voltage-gated sodium (Na+) …
Metaflumizone is a novel sodium channel blocker insecticide
VL Salgado, JH Hayashi - Veterinary parasitology, 2007 - Elsevier
Metaflumizone is a novel semicarbazone insecticide, derived chemically from the pyrazoline
sodium channel blocker insecticides (SCBIs) discovered at Philips–Duphar in the early …
sodium channel blocker insecticides (SCBIs) discovered at Philips–Duphar in the early …
Altered properties of neuronal sodium channels associated with genetic resistance to pyrethroids
Genetic resistance to pyrethroid insecticides involves nervous system insensitivity linked to
regulatory and structural genes of voltage-sensitive sodium channels. We examined the …
regulatory and structural genes of voltage-sensitive sodium channels. We examined the …
Sodium channel-directed alkaloids synergize the mosquitocidal and neurophysiological effects of natural pyrethrins
EJ Norris, JR Bloomquist - Pesticide Biochemistry and Physiology, 2022 - Elsevier
We explored the potential of two sodium channel activators, veratrine and aconitine, as both
insecticides and synergists of natural pyrethrins (NP) on Aedes aegypti adults and larvae …
insecticides and synergists of natural pyrethrins (NP) on Aedes aegypti adults and larvae …
Mapping Receptor Sites for Sodium Channel Blocking Insecticides DCJW and Metaflumizone in an Insect Sodium Channel
Y Du, Y Zhang, D Jiang, C Behnke, Y Nomura… - Biophysical …, 2016 - cell.com
Acquired pest resistance to long-used insecticides, such as sodium channel agonists DDT
and pyrethroids, motivates development of new insecticides with different mechanisms of …
and pyrethroids, motivates development of new insecticides with different mechanisms of …
Insecticides affecting voltage-gated ion channels
E Zlotkin - Biochemical sites of insecticide action and resistance, 2001 - Springer
In this chapter the term insecticides is used in its broadest sense and refers to any category
of chemical compounds (from low molecular weight organics to globular polypeptides) of …
of chemical compounds (from low molecular weight organics to globular polypeptides) of …
How does calcium-dependent intracellular regulation of voltage-dependent sodium current increase the sensitivity to the oxadiazine insecticide indoxacarb metabolite …
C Lavialle-Defaix, B Moignot, C Legros… - Journal of Pharmacology …, 2010 - ASPET
Decarbomethoxylated JW062 (DCJW), the active component of the oxadiazine insecticide
(S)-methyl 7-chloro-2, 5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy) phenyl] amino] …
(S)-methyl 7-chloro-2, 5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy) phenyl] amino] …