[HTML][HTML] COPDGene® 2019: redefining the diagnosis of chronic obstructive pulmonary disease

KE Lowe, EA Regan, A Anzueto, E Austin… - … Diseases: Journal of …, 2019 - ncbi.nlm.nih.gov
Background: Chronic obstructive pulmonary disease (COPD) remains a major cause of
morbidity and mortality. Present-day diagnostic criteria are largely based solely on …

GOLD 2011 disease severity classification in COPDGene: a prospective cohort study

MLK Han, H Muellerova, D Curran-Everett… - The lancet Respiratory …, 2013 - thelancet.com
Summary Background The 2011 GOLD (Global Strategy for the Diagnosis, Management,
and Prevention of Chronic Obstructive Pulmonary Disease [COPD]) consensus report uses …

Imaging advances in chronic obstructive pulmonary disease. Insights from the genetic epidemiology of chronic obstructive pulmonary disease (COPDGene) study

SP Bhatt, GR Washko, EA Hoffman… - American journal of …, 2019 - atsjournals.org
The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …

Chronic obstructive pulmonary disease overview: epidemiology, risk factors, and clinical presentation

JB Soriano, R Rodríguez-Roisin - Proceedings of the American …, 2011 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) has been a major public health problem
during the 20th century, and will remain a challenge for the foreseeable future. Worldwide …

New developments in the assessment of COPD: early diagnosis is key

NG Csikesz, EJ Gartman - International journal of chronic …, 2014 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is the most common chronic lung disease in
the world, and its associated health burdens and costs are mounting. Until recently, it was …

Lessons from ECLIPSE: a review of COPD biomarkers

R Faner, R Tal-Singer, JH Riley, B Celli, J Vestbo… - Thorax, 2014 - thorax.bmj.com
The Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points
(ECLIPSE) study was a large 3-year observational controlled multicentre international study …

Genetic epidemiology of COPD (COPDGene) study design

EA Regan, JE Hokanson, JR Murphy… - COPD: Journal of …, 2011 - Taylor & Francis
Background: COPDGene is a multicenter observational study designed to identify genetic
factors associated with COPD. It will also characterize chest CT phenotypes in COPD …

[HTML][HTML] Derivation and validation of clinical phenotypes for COPD: a systematic review

LM Pinto, M Alghamdi, A Benedetti, T Zaihra… - Respiratory …, 2015 - Springer
Background The traditional classification of COPD, which relies solely on spirometry, fails to
account for the complexity and heterogeneity of the disease. Phenotyping is a method that …

[HTML][HTML] Multiple biomarkers predict disease severity, progression and mortality in COPD

RL Zemans, S Jacobson, J Keene, K Kechris… - Respiratory …, 2017 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease
characterized by multiple subtypes and variable disease progression. Blood biomarkers …

Genetic advances in chronic obstructive pulmonary disease. Insights from COPDGene

MF Ragland, CJ Benway, SM Lutz… - American journal of …, 2019 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a common and progressive disease that
is influenced by both genetic and environmental factors. For many years, knowledge of the …