Influence of biofilm growth age, media, antibiotic concentration and exposure time on Staphylococcus aureus and Pseudomonas aeruginosa biofilm removal in vitro

X Chen, TR Thomsen, H Winkler, Y Xu - BMC microbiology, 2020 - Springer
Background Biofilm is known to be tolerant towards antibiotics and difficult to eradicate.
Numerous studies have reported minimum biofilm eradication concentration (MBEC) values …

Comparison of biofilm-associated cell survival following in vitro exposure of meticillin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin …

K Smith, A Perez, G Ramage, CG Gemmell… - International journal of …, 2009 - Elsevier
The efficacy of commonly used antistaphylococcal antimicrobials (clindamycin, linezolid and
vancomycin) and recently developed antibiotics (daptomycin and tigecycline) was compared …

Defining conditions for biofilm inhibition and eradication assays for Gram-positive clinical reference strains

CD Cruz, S Shah, P Tammela - BMC microbiology, 2018 - Springer
Background Biofilms are formed by a complex bacterial community encapsulated by a
polymeric matrix, with strong adherent properties and persistent phenotype. Biofilms are …

Inhibitory efficacy of various antibiotics on matrix and viable mass of Staphylococcus aureus and Pseudomonas aeruginosa biofilms

K Toté, DV Berghe, M Deschacht, K De Wit… - International journal of …, 2009 - Elsevier
Both bacteria and the matrix are essential for the development of biofilms. Antimicrobials
should therefore be tested against both components. The aim of this study was to determine …

Inefficacy of vancomycin and teicoplanin in eradicating and killing Staphylococcus epidermidis biofilms in vitro

J Claessens, M Roriz, R Merckx, P Baatsen… - International journal of …, 2015 - Elsevier
Biofilm-associated bacteria display a decreased susceptibility towards antibiotics. Routine
assessment of antibiotic susceptibility of planktonic bacteria therefore offers an insufficient …

Effect of antibiotics on biofilm inhibition and induction measured by real‐time cell analysis

MD Ferrer, JC Rodriguez, L Álvarez… - Journal of applied …, 2017 - academic.oup.com
Aims The purpose of the current work was to study the pattern and dynamics of biofilm
formation in clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis in …

Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and rifampicin against Staphylococcus aureus

WE Rose, PT Poppens - Journal of Antimicrobial Chemotherapy, 2009 - academic.oup.com
Objectives This study evaluated vancomycin susceptibility and activity alone and in
combination with rifampicin and tigecycline against low-biofilm-and high-biofilm-producing …

Antibiotic susceptibility assay for Staphylococcus aureus in biofilms developed in vitro

B Amorena, E Gracia, M Monzón, J Leiva… - Journal of …, 1999 - academic.oup.com
Four slime-producing isolates of Staphylococcus aureus were used in an antibiotic
susceptibility assay for biofilms developed on 96-well polystyrene tissue culture plates. The …

Activities of high-dose daptomycin, vancomycin, and moxifloxacin alone or in combination with clarithromycin or rifampin in a novel in vitro model of Staphylococcus …

J Parra-Ruiz, C Vidaillac, WE Rose… - Antimicrobial agents and …, 2010 - Am Soc Microbiol
Biofilm formation is an important virulence factor that allows bacteria to resist host responses
and antibacterial agents. The aim of the study was to assess the in vitro activities of several …

Biofilm Formation by Pathogenic Bacteria: Applying a Staphylococcus aureus Model to Appraise Potential Targets for Therapeutic Intervention

Z Sedarat, AW Taylor-Robinson - Pathogens, 2022 - mdpi.com
Carried in the nasal passages by up to 30% of humans, Staphylococcus aureus is
recognized to be a successful opportunistic pathogen. It is a frequent cause of infections of …