This paper reviews the body of evidence that major depression is accompanied by a
decreased antioxidant status and by induction of oxidative and nitrosative (IO&NS) …

Affective disorders are a medical condition with a complex biological pattern of etiology,
involving genetic and epigenetic factors, along with different environmental stressors …

Studies of the World Health Organization suggest that in the year 2020, depressive disorder
will be the illness with the highest burden of disease. Especially unipolar depression is the …

Major depressive disorder (MDD) affects millions of individuals and is highly comorbid with
many age-associated diseases such as diabetes mellitus, immune-inflammatory …

Depression is a medical condition with a complex biological pattern of aetiology, involving
genetic and epigenetic factors, along with different environmental stressors. Recent …

OBJECTIVE: There is evidence that major depression is characterized by oxidative and
nitrosative stress (O&NS). The aim of this study is to examine IgM-mediated autoimmune …

There is now evidence that depression, as characterized by melancholic symptoms, anxiety,
and fatigue and somatic (F&S) symptoms, is the clinical expression of peripheral cell …

There is growing evidence that the imbalance between oxidative stress and the antioxidant
defense system may be associated with the development neuropsychiatric disorders, such …

Oxidative and nitrosative stress (O&NS) could play an important role in the pathophysiology
of major depression (MDD). The aim of the present work was to evaluate the specific activity …

The brain is an organ predisposed to oxidative/nitrosative stress. This is especially true in
the case of aging as well as several neurodegenerative diseases. Under such …