Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis

F Marra, A Gastaldelli, GS Baroni, G Tell… - Trends in molecular …, 2008 - cell.com
Non-alcoholic steatohepatitis (NASH), a cause of cirrhosis and hepatocellular carcinoma, is
characterized by fatty infiltration of the liver, inflammation, hepatocellular damage and …

Pathogenesis of nonalcoholic steatohepatitis

W Liu, RD Baker, T Bhatia, L Zhu, SS Baker - Cellular and Molecular Life …, 2016 - Springer
Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease and
a risk factor for cirrhosis and hepatocellular carcinoma. The pathological features of NASH …

Molecular pathogenesis of NASH

A Caligiuri, A Gentilini, F Marra - International journal of molecular …, 2016 - mdpi.com
Nonalcoholic steatohepatitis (NASH) is the main cause of chronic liver disease in the
Western world and a major health problem, owing to its close association with obesity …

Comprehensive molecular mechanisms and clinical therapy in nonalcoholic steatohepatitis: an overview and current perspectives

M Yan, S Man, L Ma, W Gao - Metabolism, 2022 - Elsevier
Our understanding of nonalcoholic steatohepatitis (NASH) pathophysiology continues to
advance rapidly. Given the complexity of the pathogenesis of NASH, the field has moved …

The metabolic basis of nonalcoholic steatohepatitis

MV Chakravarthy… - … , diabetes & metabolism, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease and is
associated with significant morbidity and mortality worldwide, with a high incidence in …

[HTML][HTML] The cellular pathways of liver fibrosis in non-alcoholic steatohepatitis

N Méndez-Sánchez, A Valencia-Rodríguez… - Annals of …, 2020 - ncbi.nlm.nih.gov
Non-alcoholic steatohepatitis (NASH) is considered the advanced stage of non-alcoholic
fatty liver disease (NAFLD). It is characterized by liver steatosis, inflammation and different …

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

G Musso, M Cassader, R Gambino - Nature reviews Drug discovery, 2016 - nature.com
Non-alcoholic fatty liver disease—the most common chronic liver disease—encompasses a
histological spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) …

Recent insights into the pathogenesis of nonalcoholic fatty liver disease

JP Arab, M Arrese, M Trauner - Annual Review of Pathology …, 2018 - annualreviews.org
Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem worldwide and an
important risk factor for both hepatic and cardiometabolic mortality. The rapidly increasing …

Progressive liver fibrosis in non-alcoholic fatty liver disease

D Ramai, A Facciorusso, E Vigandt, B Schaf… - Cells, 2021 - mdpi.com
Non-alcoholic steatohepatitis (NASH) is a chronic and progressive form of non-alcoholic
fatty liver disease. Its global incidence is increasing and makes NASH an epidemic and a …

[PDF][PDF] Mechanisms and disease consequences of nonalcoholic fatty liver disease

R Loomba, SL Friedman, GI Shulman - Cell, 2021 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …