[HTML][HTML] Risk factors for chronic cerebrospinal venous insufficiency (CCSVI) in a large cohort of volunteers

K Dolic, B Weinstock-Guttman, K Marr, V Valnarov… - PLoS …, 2011 - journals.plos.org
Background The role of intra-and extra-cranial venous system impairment in the
pathogenesis of various vascular, inflammatory and neurodegenerative neurological …

CCSVI is associated with multiple sclerosis

S Morovic, P Zamboni - Neurological research, 2012 - Taylor & Francis
Objectives: To analyze all the arguments against chronic cerebrospinal venous insufficiency
(CCSVI) as a medical entity, and its association with multiple sclerosis (MS) and to revise all …

[HTML][HTML] Chronic cerebrospinal venous insufficiency is not associated with multiple sclerosis and its severity: a blind-verified study

MA Leone, O Raymkulova, P Naldi, P Lochner… - PLoS …, 2013 - journals.plos.org
Background Chronic Cerebrospinal Venous Insufficiency (CCSVI) has been associated with
multiple sclerosis (MS) with a risk ranging from as high as two-hundred-fold to a protective …

The hypothesis of pathophysiological correlation between chronic cerebrospinal venous insufficiency and multiple sclerosis: rationale of treatment

M Lugli, M Morelli, S Guerzoni, O Maleti - Phlebology, 2012 - journals.sagepub.com
Background: The possible role of the venous system in the pathogenesis of chronic
neurodegenerative diseases has been hypothesized for decades. Quite recently, the …

[HTML][HTML] Multiple sclerosis and CCSVI: a population-based case control study

F Patti, A Nicoletti, C Leone, S Messina, E D'Amico… - 2012 - journals.plos.org
Background Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to
multiple sclerosis (MS). Objective To evaluate the possible association between CCSVI and …

[HTML][HTML] Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study

IW Rodger, D Dilar, J Dwyer, J Bienenstock, A Coret… - PLoS …, 2013 - journals.plos.org
Objective Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS.
Recently a controversial vascular hypothesis for MS, termed chronic cerebrospinal venous …

[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: a historical perspective

MD Dake, R Zivadinov, EM Haacke - Functional neurology, 2011 - ncbi.nlm.nih.gov
Chronic cerebrospinal venous insufficiency (CCSVI) is a term used to describe impaired
venous drainage from the central nervous system (CNS) caused by abnormalities in …

[HTML][HTML] Clinical correlates of chronic cerebrospinal venous insufficiency in multiple sclerosis

B Weinstock-Guttman, M Ramanathan, K Marr… - BMC neurology, 2012 - Springer
Background Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition
characterized by anomalies of the primary veins outside the skull that has been reported to …

Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study

G Comi, MA Battaglia, A Bertolotto… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a
possible cause of multiple sclerosis (MS). Objectives: The CoSMo study evaluated the …

Chronic cerebrospinal venous insufficiency and multiple sclerosis: a comprehensive meta-analysis of case–control studies

G Tsivgoulis, TN Sergentanis, A Chan… - Therapeutic …, 2014 - journals.sagepub.com
Objectives: Chronic cerebrospinal venous insufficiency (CCSVI) has recently been
implicated in the pathogenesis of multiple sclerosis (MS). This comprehensive meta-analysis …