The number of antigen-specific naive CD8+ T cells is believed to be important in the shaping
of adaptive immune responses, and is predictive for the magnitude of priming responses in …

Alloreactive T cell precursor frequency was measured in vivo using fluorescent dye labeling
in combination with novel models based on lymphocyte activation and recovery. CFSE …

The identification and study of antigen-specific CD4 T cells, both in peripheral blood and in
tissues, is key for a broad range of immunological research, including vaccine responses …

The preexisting HIV-1–specific T cell repertoire must influence both the immunodominance
of T cells after infection and immunogenicity of vaccines. We directly compared two methods …

A primary goal of cancer immunotherapy is to improve the naturally occurring, but weak,
immune response to tumors. Ineffective responses to cancer vaccines may be caused, in …

Proper transcriptional control of pro-and anti-inflammatory responses of the immune system
is important for a fine-tuned balance between protection and tolerance. Emerging evidence …

The ability to measure proliferation of rare antigen-specific T cells among many bystanders
is critical for the evaluation of cellular immune function in health and disease. T-cell …

The differentiation of CD4+ or CD8+ T cells following priming of naive cells is central in the
establishment of the immune response against pathogens or tumors. However, our …

Basic parameters of the naive antigen (Ag)‐specific T‐cell repertoire in humans remain
poorly defined. Systematic characterization of this 'ground state'immunity in comparison with …

Antigen-responsive CD4+ T cell clones contribute to the HIV-1 latent reservoir | Journal of
Experimental Medicine | Rockefeller University Press Skip to Main Content Advertisement …